Indications for XYZAL ORAL SOLUTION:

Seasonal allergic rhinitis (for patients ≥2 years old). Perennial allergic rhinitis, chronic idiopathic urticaria (for patients ≥6 months old).

Adult Dose for XYZAL ORAL SOLUTION:

2.5mg–5mg once daily in the PM. Renal dysfunction: CrCl 50–80mL/min: 2.5mg once daily; CrCl 30–50mL/min: 2.5mg every other day; CrCl 10–30mL/min: 2.5mg twice per week (every 3–4 days); CrCl <10mL/min or hemodialysis: contraindicated.

Children's Dose for XYZAL ORAL SOLUTION:

<6mos: not recommended. 6mos–5yrs: max 1.25mg once daily in the PM. 6–11yrs: max 2.5mg once daily in the PM. Renal dysfunction: contraindicated.

See Also:

XYZAL

Pharmacological Class:

Antihistamine.

Contraindications:

End-stage renal disease (CrCl <10mL/min) or hemodialysis. Impaired renal function (<12yrs of age).

Warnings/Precautions:

Do not exceed recommended dose. Predisposing factors of urinary retention (eg, spinal cord lesion, prostatic hyperplasia). Discontinue if urinary retention occurs. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Avoid alcohol, other CNS depressants. May be potentiated by theophylline. Potentiated by ritonavir.

Adverse Reactions:

Adults: somnolence, nasopharyngitis/pharyngitis, fatigue, dry mouth. Children: pyrexia, somnolence, cough, epistaxis, diarrhea, constipation, vomiting, otitis media.

Metabolism:

Hepatic (minimal).

Elimination:

Renal (primarily), fecal.

Generic Availability:

YES

How Supplied:

Tabs—90; Soln—150mL