Generic Name and Formulations:
Leva lbuterol (as HCl) (single-isomer albuterol) 1.25mg/0.5mL; per vial; soln for inhalation via nebulization after dilution; preservative-free.

Company:
Sunovion

Indications for XOPENEX CONCENTRATE:
Bronchospasm.

Adult Dose for XOPENEX CONCENTRATE:
Initially 0.63mg by nebulization 3 times daily at 6–8 hr intervals; may increase to 1.25mg 3 times daily.

Children's Dose for XOPENEX CONCENTRATE:
<6yrs: not established. 6–11yrs: 0.31mg by nebulization 3 times daily; max 0.63mg 3 times daily.

See Also:
XOPENEX

XOPENEX HFA

Pharmacological Class:
beta-2 agonist.

Warnings/Precautions:
Do not exceed recommended dose; monitor for increased need. Sensitivity to sympathomimetics. Discontinue if paradoxical bronchospasm or cardiovascular effects occur. Cardiovascular disease (esp. coronary insufficiency, arrhythmias, hypertension). Seizure disorders. Diabetes. Hyperthyroidism. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:
Avoid within 2 weeks of MAOIs, tricyclic antidepressants. Avoid other short-acting sympathomimetic aerosol bronchodilators, epinephrine. Antagonized by β-blockers. Monitor digoxin. Caution with other drugs that may lower serum potassium (eg, diuretics).

Adverse Reactions:
Accidental injury, bronchitis, dizziness, nervousness, tremor, pain, pharyngitis, rhinitis, vomiting; paradoxical bronchospasm, hypersensitivity reactions, cardiovascular effects, hypokalemia.

Generic Availability:
Vials (YES); HFA (NO)

How Supplied:
Inhaler w. actuator (80inh)—8.4g, (200 inh)—15g; Soln 0.31mg/3mL, 0.63mg/3mL, 1.25mg/3mL—24 vials; Concentrate 1.25mg/0.5mL—30 vials