Keppra用作局部发作性癫痫症成人患者的辅助治疗药。之前，它已具备片剂和口服液两种剂型，刚获准的注射剂将在癫痫症急性发作时使用。

Keppra已成为UCB最热销的药物，而它的注射剂将进一步推动其销量。Generic Name for KEPPRA INJECTION
Levetiracetam 100mg/mL; IV infusion after dilution.

Legal Classification:
Rx
Manufacturer of KEPPRA INJECTION
UCB Inc.

Indications for KEPPRA INJECTION
Use when oral administration is temporarily not feasible: as adjunct in partial onset seizures; and adjunct in myoclonic seizures in patients with juvenile myoclonic epilepsy.

Adult dose for KEPPRA INJECTION
≥16yrs: Infuse over 15 minutes. Partial onset: Initially 500mg twice daily; may increase at 2-week intervals in increments of 1g/day; max 3g/day. Myoclonic: Initially 500mg twice daily; increase at 2-week intervals in increments of 1g/day to target dose of 3g/day. Renal impairment: CrCl 50–80mL/min: 500mg–1g every 12 hours; CrCl 30–50mL/min: 250–750mg every 12 hours; CrCl <30mL/min: 250–500mg every 12 hours; ESRD patients on dialysis: 500mg–1g every 24 hours and a supplement of 250–500mg post-dialysis.

Children's dosing for KEPPRA INJECTION
<16yrs: not recommended.

Also:
KEPPRA
KEPPRA ORAL SOLUTION
KEPPRA XR
Warnings/Precautions for KEPPRA INJECTION
Renal impairment. Suicidal tendencies (monitor). Avoid abrupt cessation. Elderly (consider monitoring renal function). Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Adverse Reactions for KEPPRA INJECTION
Somnolence, asthenia, infection, dizziness, coordination difficulties (eg, ataxia, abnormal gait), mood and behavioral abnormalities (eg, irritability, anger, depression, anxiety, apathy), neck pain, pharyngitis, hematologic abnormalities; rare: psychotic symptoms. Children: also accidental injury, hostility, nervousness. XR: also nausea.

Notes for KEPPRA INJECTION
Register pregnant patients exposed to levetiracetam by calling (888) 537-7734.
How is KEPPRA INJECTION supplied?
Tabs 250mg, 500mg, 750mg—120
1000mg—60
XR—60
Soln—pt
Single-use vials (5mL)—10

通用名称为注射Keppra，Enbrel作者
左乙拉西坦100mg/mL;稀释后静脉滴注。

法律分类：
接收
Keppra，Enbrel作者注射液制造商
联合银行公司

Keppra，Enbrel作者适应症注射
时使用口服暂不可行的：如在局部发作的辅助以及在青少年肌阵挛性肌阵挛性癫痫患者在发作的辅助治疗。

成人剂量注射Keppra，Enbrel作者
≥16yrs：注入超过15分钟。部分发作：最初500毫克，每天两次;可能增加的1g/day增量在2周的时间间隔，最大3g/day。肌阵挛性：最初500毫克每日两次的1g/day增量在2周的时间间隔增加目标3g/day剂量。肾功能损害：肌酐清除率50-80mL/min：500毫克，1克，每12小时; CrCl为30-50mL/min：250 - 750mg，每12小时肌酐清除率<30mL/min：250 - 500毫克，每12小时;终末期肾病透析患者：500毫克- 1G型每24小时和250 - 500mg的后透析补充。

儿童注射剂量为Keppra，Enbrel作者
<16yrs：不推荐。

另外：
Keppra，Enbrel作者
Keppra，Enbrel作者口服液
XR的Keppra，Enbrel作者
警告/ Keppra，Enbrel作者注射的注意事项
肾功能损害。自杀倾向（监视器）。避免突然停止。老人（考虑监测肾功能）。劳动和交付。妊娠（Cat.C）。哺乳母亲：不推荐。
Keppra，Enbrel作者注射液不良反应的
嗜睡，无力，感染，头晕，协调困难（例如，共济失调，异常步态），情绪和行为异常（如烦躁，愤怒，抑郁，焦虑，冷漠），颈部疼痛，咽炎，血液异常;罕见：精神病症状。孩子们：还意外受伤，敌意，紧张。 XR的：还恶心。

Keppra，Enbrel作者注射须知
注册怀孕患者接触到左乙拉西坦致电（888）537-7734。
Keppra，Enbrel作者注射液是如何提供？
制表250毫克，500毫克，750mg - 120
1000毫克- 60
的XR - 60
溶液铂
单用小瓶（5毫升）-10