Uncommon: Ringing noise in ears; change of bowel habit; pain; weight decrease; joint pain; trembling; mood swings; urination disorders; urination at night; breast enlargement in men; runny nose; hair loss; skin eruption; purple skin patches; rash; skin discoloration.
Very rare: Low level of white blood cells and blood platelets; irregular heart beat; heart attack; inflammation of the stomach lining or of the pancreas, gingival overgrowth, abnormal liver function test; liver disorder which can occur together with yellow skin and eyes, or dark-coloured urine; allergic reaction including swelling deeper in the skin and difficulty breathing; high level of sugar in the blood; increased muscle stiffness; skin reaction with skin reddening and peeling, blistering of lips, eyes or mouth; itchy rash; inflammation of blood vessels.
Not known: Stiff limbs and trembling hands.
Valsartan Not known: Abnormal red blood cell test; low level of a certain type of white blood cell and blood platelet; increase of potassium in the blood; increase of creatinine in the blood; abnormal liver function test; allergic reaction including swelling deeper in the skin and difficulty breathing; muscle pain; severely decreased urine output; itching; rash; inflammation of blood vessels.
Hydrochlorothiazide Common: Increase of lipids in the blood.
Uncommon: Low level of magnesium in the blood; rash; itchy rash.
Rare: Low level of blood platelets, sugar in the urine; high level of sugar in the blood; depression; irregular heart beat; abdominal discomfort; constipation; liver disorder which can occur together with yellow skin and eyes, or dark-coloured urine; increased sensitivity of skin to sun; purple skin patches. Very rare: Lack or low level of white blood cells; haemolytic anaemia (abnormal breakdown of red blood cells either in the blood vessels or elsewhere in the body); inflammation of the pancreas; allergic reaction; difficulty breathing, breathlessness; inflammation of the lungs, lupus erythematosus; inflammation of blood vessels; severe skin disease that causes rash, red skin, blistering of the lips, eyes or mouth, skin peeling, fever.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
How should it be stored?
Keep out of the reach and sight of children.
Do not use Exforge HCT after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month.
Do not store above 30°C.
Store in the original package in order to protect from moisture.
Do not use any Exforge HCT pack that is damaged or shows signs of tampering.
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For doctors
What is it?
Exforge HCT is a medicine that contains three active substances, amlodipine, valsartan and hydrochlorothiazide. It is available as tablets containing amlodipine, valsartan and hydrochlorothiazide in the following amounts: 5/160/12.5 mg, 10/160/12.5 mg, 5/160/25 mg, 10/160/25 mg and 10/320/25 mg.
What is it used for?
Exforge HCT is used to treat essential hypertension (high blood pressure) in adults whose blood pressure is already adequately controlled with a combination of amlodipine, valsartan and hydrochlorothiazide. ‘Essential
