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DAURISMOTM(glasdegib)tablets, for oral(十四)
2018-11-24 13:52:05 来源: 作者: 【 】 浏览:9320次 评论:0
fter your last dose to protect your female partner from being exposed to DAURISMO.
Tell your healthcare provider right away if your partner becomes pregnant or thinks she is pregnant while you are
taking DAURISMO.
Exposure to DAURISMO during pregnancy:
If you think that you or your female partner may have been exposed to DAURISMO during pregnancy, talk to yourhealthcare provider right away. If you become pregnant during treatment with DAURISMO, you or your healthcareprovider should report your pregnancy to Pfizer at 1-800-438-1985.
What is DAURISMO?
DAURISMO is a prescription medicine that is used with the medicine cytarabine to treat newly-diagnosed acutemyeloid leukemia (AML) in adults who:
are 75 years of age or older, orhave other medical conditions that prevent the use of standard chemotherapyDAURISMO has not been studied in people with severe kidney problems or moderate-to-severe liver problems.
It is not known if DAURISMO is safe and effective in children.
Before you take DAURISMO, tell your healthcare provider about all of your medical conditions, including ifyou:
have heart problems, including a condition called long QT syndrome.
abnormal blood salt (electrolytes) levels.
are pregnant or plan to become pregnant. See “What is the most important information I should know aboutDAURISMO?”
are breastfeeding or plan to breastfeed. It is not known if DAURISMO passes into your breast milk. Do notbreastfeed or provide breast milk to infants or children during treatment with DAURISMO and for at least 30 daysafter the last dose. Talk to your healthcare provider about the best way to feed your baby during this time.
Tell your healthcare provider about the medicines you take, including prescription medicines, over-the-countermedicines, vitamins, and herbal supplements.
How should I take DAURISMO?
Take DAURISMO with the medicine cytarabine exactly as your healthcare provider tells you.
Take DAURISMO 1 time each day, at about the same time each day.
Take DAURISMO with or without food.
Do not chew, split or crush DAURISMO tablets.
If you miss a dose, take it as soon as you remember. If it is less than 12 hours before your next dose, just skip themissed dose and take your next dose at your regular time. Do not take 2 doses of DAURISMO within 12 hours.
If you vomit after taking a dose of DAURISMO, do not take an extra dose, just take your next dose at your regulartime.
Your healthcare provider will perform certain tests to check you for side effects before and during treatment withDAURISMO.
Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with DAURISMOif you have certain side effects. Do not change your dose or stop taking DAURISMO unless your healthcare
provider tells you.
What should I avoid while taking DAURISMO?
Do not donate blood or blood products during treatment with DAURISMO and for at least 30 days after the lastdose.
 Do not donate semen during treatment with DAURISMO and for at least 30 days after the last dose.
What are the possible side effects of DAURISMO?
DAURISMO can cause serious side effects, including:
See “What is the most important information I should know about DAURISMO?”
Changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregularheartbeats that can be life-threatening. Tell your healthcare provider right away if you feel faint, lightheaded, dizzy,o
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