nbsp; Stomatitis, Ulcerative Stomatitis, Mucositis 14 1
Abdominal Pain 11 2
Dyspepsia 10 --
Constipation 9 1
Hematologic Disorders
WBC Disorders: Neutropenia 85 64
RBC Disorders: Anemia 80 38
Pancytopenia 5 3
Platelet, Bleeding & Clotting Disorders:
Thrombocytopenia 72 50
Purpura 8 --
Epistaxis 7 1
Musculoskeletal Disorders
Myalgias 11 --
Psychiatric Disorders
Insomnia 10 --
Depression 7 1
Somnolence 5 1
Resistance Mechanism Disorders
Sepsis 15 10
Herpes Simplex 11 1
Moniliasis 8 1
Infection (other viral or unidentified) 7 1
Respiratory System Disorders
Dyspnea 26 9
Cough 25 2
Bronchitis, Pneumonitis 21 13
Pneumonia 16 10
Pharyngitis 12 --
Bronchospasm 9 2
Rhinitis 7 --
Skin & Appendage Disorders
Rash, Maculopapular Rash, Erythematous Rash 40 3
Urticaria 30 5
Pruritus 24 1
Sweating increased 19 1
Serious adverse events:
The following serious adverse events, defined as events which result in death, requiring or prolonging hospitalization, requiring medical intervention to prevent hospitalization, or malignancy, were reported in at least one patient treated on studies where Campath was used as a single agent (and are not reported in Table 2). These studies were conducted in patients with lymphocytic leukemia and lymphoma (N = 745) and in patients with non-malignant diseases (N =152) such as rheumatoid arthritis, solid organ transplant, or multiple sclerosis.
Body As A Whole: allergic reactions, anaphylactoid reaction, ascites, hypovolemia, influenza-like syndrome, mouth edema, neutropenic fever, syncope
Cardiovascular Disorders: cardiac failure, cyanosis, atrial fibrillation, cardiac arrest, ventricular arrhythmia, ventricular tachycardia, angina pectoris, coronary artery disorder, myocardial infarction, pericarditis
Central and Peripheral Nervous System Disorders: abnormal gait, aphasia, coma, grand mal convulsions, para |
