At present it is not known how long treatment with Extavia should last. The length of treatment will be decided by your doctor together with you.

If you use more Extavia than you should

Giving many times the dose of Extavia recommended for the treatment of multiple sclerosis has not led to life-threatening situations.

Talk to your doctor if you inject too much Extavia or injected too often.

If you forget to use Extavia

If you have forgotten to give yourself an injection at the right time do it as soon as you remember and then follow on with the next one 48 hours later.

Do not inject a double dose to make up for a forgotten individual dose.

If you stop using Extavia

Talk to your doctor if you stop or wish to stop treatment. Stopping Extavia is not known to cause acute withdrawal symptoms.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

What are possible side effects?

Like all medicines, Extavia can cause side effects, although not everybody gets them.

At the beginning of treatment side effects are common but in general they become less with further treatment.

The most common side effects are:

Flu-like symptoms such as fever, chills, painful joints, malaise, sweating, headache, or muscular pain. These symptoms may be reduced by taking paracetamol or non-steroidal anti-inflammatory medicines such as ibuprofen.

Injection site reactions. Symptoms can be redness, swelling, discolouration, inflammation, pain, hypersensitivity, necrosis. See Take special care in section 2 for more information and what to do if you experience an injection site reaction. These may be reduced by the use of an auto-injector device. Please talk to your doctor for further information.

To reduce side effects at the start of treatment, your doctor should start you on a low dose of Extavia and increase it gradually (see section 3, ?How to use Extavia?).

Extavia may also cause serious side effects. If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Tell your doctor immediately and stop using Extavia

◾if you experiencesymptoms such as itching all over your body, swelling of your face and/or your tongue or sudden shortness of breath.

◾if you feel noticeably more sad or hopeless than before the treatment with Extavia, or if you develop thoughts of suicide.

◾if you notice any unusual bruising, excessive bleeding after injury or if you seem to be catching a lot of infections.

◾if you have loss of appetite, fatigue, feeling sick(nausea), repeated vomiting, especially if you notice widespread itching, yellowing of the skin, or of the whites of the eyes or easy bruising.

◾if you experience symptoms like irregular heart beat, swelling such as of the ankles or legs, or shortness of breath.

◾if you notice pain in your belly which is radiating to your back , and/or you feel sick or have a fever.

The following side effects listing is based on reports from clinical trials with Extavia (List 1)and from side effects reported on the marketed product (List 2).