increasing shortness of breath or trouble breathing, especially when you lie down

swelling or fluid retention, especially in the feet, ankles or legs

an unusually fast increase in weight

unusual tiredness

These may be symptoms of heart failure.

What is STEGLUJAN? 

STEGLUJAN contains 2 prescription diabetes medicines called ertugliflozin (STEGLATRO™) and sitagliptin (JANUVIA®). STEGLUJAN can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

STEGLUJAN is not for people with type 1 diabetes.

STEGLUJAN is not for people with diabetic ketoacidosis (increased ketones in your blood or urine).

If you have had pancreatitis (inflammation of the pancreas) in the past, it is not known if you have a higher chance of getting pancreatitis while you take STEGLUJAN.

It is not known if STEGLUJAN is safe and effective in children under 18 years of age.

Do not take STEGLUJAN if you: 

have severe kidney problems or are on dialysis.

are allergic to ertugliflozin, sitagliptin, or any of the ingredients in STEGLUJAN. See the end of this Medication Guide for a list of ingredients in STEGLUJAN. Symptoms of a serious allergic reaction to STEGLUJAN may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing.

Before you take STEGLUJAN, tell your doctor about all of your medical conditions, including if you: 

have type 1 diabetes or have had diabetic ketoacidosis.

have kidney problems.

have liver problems.

have or have had problems with your pancreas, including pancreatitis or surgery on your pancreas.

have a history of urinary tract infections or problems with urination.

are eating less due to illness, surgery, or a change in your diet.

have a history of amputation.

have had blocked or narrowed blood vessels, usually in the leg.

have damage to the nerves (neuropathy) in your leg.

have had diabetic foot ulcers or sores.

are going to have surgery.

drink alcohol very often, or drink a lot of alcohol in the short term ("binge" drinking).

are pregnant or plan to become pregnant. STEGLUJAN may harm your unborn baby. If you become pregnant while taking STEGLUJAN, your doctor may switch you to a different medicine to control your blood sugar. Talk to your doctor about the best way to control your blood sugar if you plan to become pregnant or while you are pregnant.

Pregnancy Registry: If you take STEGLUJAN at any time during your pregnancy, talk with your doctor about how you can join the STEGLUJAN pregnancy registry. The purpose of this registry is to collect information about the health of you and your baby. You can enroll in this registry by calling 1-800-986-8999.

are breastfeeding or plan to breastfeed. It is not known if STEGLUJAN passes into your breast milk. You should not breastfeed if you take STEGLUJAN.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. 

How should I take STEGLUJAN? 

Take STEGLUJAN exactly as your doctor tells you to take it.

Take STEGLUJAN by mouth 1 time in the morning each day, with or without food.

Your doctor may change your dose if needed.