ections.
Using a syringe fitted with a needle, aseptically withdraw 1.5 ml of sterile water for injections. Inject the content of the syringe into the vial through the rubber stopper.
Remove the syringe and the needle and mix manually by repeated inversions.
Only clear colourless solutions, without any particulate matter, must be used.
Further dilution in the infusion bag
The reconstituted solution is hypotonic and should be further diluted prior to administration with 500 ml sodium chloride 9 mg/ml (0.9%) solution for injection.
Administration
TEPADINA infusion solution should be inspected visually for particulate matter and opalescence prior to administration. Solutions containing a precipitate should be discarded.
It is recommended that the infusion solution be administered to patients using an infusion set equipped with a 0.2 µm in-line filter.
TEPADINA should be aseptically administered as a 2-4 hours infusion under room temperature and normal light conditions.
Prior to and following each infusion, the indwelling catheter line should be flushed with approximately 5 ml sodium chloride 9 mg/ml (0.9%) solution for injection.
Disposal
TEPADINA is for single use only.
Any unused product or waste material should be disposed of in accordance with local requirements. |
