matory drugs (NSAIDs)
warfarin sodium (Coumadin®, Jantoven®)
any medicine that contains heparin
selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs)
other medicines to prevent or treat blood clots
P-glycoprotein (P-gp) inhibitors
Tell your healthcare provider if you take any of these medicines. Ask your healthcare provider or pharmacist if you are not sure if your medicine is one listed above.
While taking BEVYXXA:
you may bruise more easily
it may take longer than usual for any bleeding to stop
Call your healthcare provider or get medical help right away if you have any of these signs or symptoms of bleeding when taking BEVYXXA:
unexpected bleeding, or bleeding that lasts a long time such as:
unusual bleeding from the gums
nosebleeds that happen often
menstrual bleeding or vaginal bleeding that is heavier than normal
bleeding that is severe or you cannot control
red, pink, or brown urine
red or black stools (looks like tar)
cough up blood or blood clots
vomit blood or your vomit looks like coffee grounds
unexpected pain, swelling, or joint pain
headaches, feeling dizzy or weak
Spinal or epidural blood clots (hematoma). People who take a blood thinner medicine (anticoagulant) like BEVYXXA, and have medicine injected into their spinal and epidural area, or have a spinal puncture have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis). Your risk of developing a spinal or epidural blood clot is higher if:
a thin tube called an epidural catheter is placed in your back to give you certain medicine
you take NSAIDs or a medicine to prevent blood from clotting
you have a history of difficult or repeated epidural or spinal punctures
you have a history of problems with your spine or have had surgery on your spine
If you take BEVYXXA and receive spinal anesthesia or have a spinal puncture, your healthcare provider should watch you closely for symptoms of spinal or epidural blood clots. Tell your healthcare provider right away if you have back pain, tingling, numbness (especially in your legs and feet), muscle weakness, or loss of control of the bowels or bladder (incontinence).
See "WHAT ARE THE POSSIBLE SIDE EFFECTS OF BEVYXXA?" for more information about side effects.
What is BEVYXXA?
BEVYXXA is a prescription medicine used to help prevent blood clots in adults who are hospitalized for an acute illness, and are at risk of getting blood clots because of the loss of or decreased ability to move around (mobility) and other risks for getting blood clots.
It is not known if BEVYXXA is safe and effective in people with artificial heart valves.
It is not known if BEVYXXA is safe and effective in children.
Do not take BEVYXXA if you:
have bleeding problems. Tell your healthcare provider if you have, or are at risk for, bleeding problems.
are allergic to betrixaban or to any of the ingredients in BEVYXXA. See the end of this Medication Guide for a complete list of ingredients in BEVYXXA.
Before taking BEVYXXA, tell your healthcare provider about all your medical conditions, including if you:
have liver or kidney problems
have ever had bleeding problems
have an artificial heart valve
are pregnant or plan to become pregnant. It is not known if BEVYXXA will harm your unborn baby. Taking BEVYXXA may increase the risk of bleeding during pregnancy and delivery.
are breastfeeding or plan to breastfeed. It is not known if BEVYXXA pa |
