if you take:
•any other medicines to treat your rheumatoid arthritis. You should not take tocilizumab (Actemra®), etanercept (Enbrel®), adalimumab (Humira®), infliximab (Remicade®), rituximab (Rituxan®), abatacept (Orencia®), anakinra (Kineret®), certolizumab (Cimzia®), golimumab (Simponi®), azathioprine, cyclosporine, or other immunosuppressive drugs while you are taking XELJANZ. Taking XELJANZ with these medicines may increase your risk of infection.
•medicines that affect the way certain liver enzymes work. Ask your healthcare provider if you are not sure if your medicine is one of these.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
How should I take XELJANZ?
•Take XELJANZ as your healthcare provider tells you to take it.
•Take XELJANZ 2 times a day with or without food.
•If you take too much XELJANZ, call your healthcare provider or go to the nearest hospital emergency room right away.
What are possible side effects of XELJANZ?
XELJANZ may cause serious side effects, including:
•See "What is the most important information I should know about XELJANZ?"
• Hepatitis B or C activation infection in people who carry the virus in their blood. If you are a carrier of the hepatitis B or C virus (viruses that affect the liver), the virus may become active while you use XELJANZ. Your healthcare provider may do blood tests before you start treatment with XELJANZ and while you are using XELJANZ. Tell your healthcare provider if you have any of the following symptoms of a possible hepatitis B or C infection:
◦feel very tired
◦skin or eyes look yellow
◦little or no appetite
◦vomiting
◦clay-colored bowel movements
◦fevers
◦chills
◦stomach discomfort
◦muscle aches
◦dark urine
◦skin rash
Common side effects of XELJANZ include:
•upper respiratory tract infections (common cold, sinus infections)
•headache
•diarrhea
•nasal congestion, sore throat, and runny nose (nasopharyngitis)
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of XELJANZ. For more information, ask your healthcare provider or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
You may also report side effects to Pfizer at 1-800-438-1985.
How should I store XELJANZ?
Store XELJANZ at 68°F to 77°F (room temperature).
Safely throw away medicine that is out of date or no longer needed.
Keep XELJANZ and all medicines out of the reach of children.
General information about the safe and effective use of XELJANZ.
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use XELJANZ for a condition for which it was not prescribed. Do not give XELJANZ to other people, even if they have the same symptoms you have. It may harm them.
This Medication Guide summarizes the most important information about XELJANZ. If you would like mor
