hen you get a new medicine.
How should I take ZURAMPIC?
•Take ZURAMPIC exactly as your healthcare provider tells you to take it.
•Take 1 ZURAMPIC tablet in the morning with your dose of xanthine oxidase inhibitor such as allopurinol or febuxostat. Do not take more than 1 ZURAMPIC tablet each day.
•Take ZURAMPIC with food and water.
•Drink 2 liters (68 ounces) of fluid each day to stay hydrated.
•If you miss taking the dose of ZURAMPIC in the morning, do not take ZURAMPIC later in the day. Wait and take your next dose of ZURAMPIC in the morning with your dose of xanthine oxidase inhibitor such as allopurinol or febuxostat. Do not double your dose of ZURAMPIC.
•Your gout may get worse (flare up) when you first start taking ZURAMPIC. Do not stop taking ZURAMPIC even if you have a flare. Your healthcare provider may give you other medicines to help prevent your gout flares.
•Your healthcare provider may do blood tests to check how well your kidneys are working before and during your treatment with ZURAMPIC.
What should I avoid while taking ZURAMPIC?
•Avoid taking ZURAMPIC alone. This could increase your risk of kidney problems. ZURAMPIC should always be taken together with a xanthine oxidase inhibitor such as allopurinol or febuxostat.
•Avoid becoming dehydrated while taking ZURAMPIC.
What are the possible side effects of ZURAMPIC?
ZURAMPIC may cause serious side effects, including:
•See “What is the most important information I should know about ZURAMPIC?”
•heart problems. People who take ZURAMPIC can have serious heart problems including heart attack and stroke. It is not known that ZURAMPIC causes these problems.
The most common side effects of ZURAMPIC include:
•headache
•flu
•higher levels of blood creatinine (a measure of kidney function)
•heart burn (acid reflux)
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of ZURAMPIC. For more information, ask your healthcare provider or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How should I store ZURAMPIC?
•Store ZURAMPIC at room temperature between 68°F to 77°F (20°C to 25°C).
•Keep ZURAMPIC away from light.
Keep ZURAMPIC and all medicines out of the reach of children.
General Information about the safe and effective use of ZURAMPIC.
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use ZURAMPIC for a condition for which it was not prescribed. Do not give ZURAMPIC to other people, even if they have the same symptoms that you have. It may harm them.
This Medication Guide summarizes the most important information about ZURAMPIC. If you would like more information about ZURAMPIC, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about ZURAMPIC that is written for healthcare professionals.
What are the ingredients in ZURAMPIC?
Active ingredient: lesinurad
Inactive ingredients: lactose monohydrate, microcrystalline cellulose, hypromellose, crospovidone, and magnesium stearate.
Manufactured for: AstraZeneca Pharmaceuticals LP, Wilmington, DE 19850; Manufactured by: AstraZeneca AB, S-151 85 Södertälje, Sweden
ZURAMPIC is a trademark of the AstraZeneca group of co |
