u take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Vandetanib and other medicines may affect each other causing side effects.
Especially tell your healthcare provider if you take:
•St. John’s Wort. You should not take St. John’s Wort while taking Vandetanib.
•certain medicines that can affect how your liver breaks down medicine
•a medicine for your heart
Ask your healthcare provider if you are not sure if your medicine is one listed above.
Do not take other medicines while taking Vandetanib until you have talked with your healthcare provider or pharmacist.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
How should I take Vandetanib?
•Take Vandetanib exactly as your healthcare provider tells you to take it. Do not change your dose or stop taking Vandetanib unless your healthcare provider tells you to.
•Vandetanib may be taken with or without food.
•Swallow Vandetanib tablets whole with water.
•Do not crush or chew Vandetanib tablets. If Vandetanib tablets are accidentally crushed, contact with skin should be avoided. If contact occurs, wash affected areas well with water.
•If you cannot swallow Vandetanib tablets whole:
◦place your dose of Vandetanib in a glass that contains 2 ounces of noncarbonated water (no other liquids should be used).
◦stir the Vandetanib tablet(s) and water mixture for about 10 minutes or until the tablet(s) are in very small pieces (the tablets will not completely dissolve).
◦swallow Vandetanib and water mixture right away.
◦if any Vandetanib and water mixture remains in the glass, mix with an additional 4 ounces of noncarbonated water and swallow the mixture to make sure that you take your full dose of Vandetanib.
•If you miss a dose and your next dose is in:
◦less than 12 hours, take your next dose at the normal time. Do not make up for the missed dose.
◦12 hours or more, take the missed dose as soon as you remember. Take the next dose at the normal time.
Call your healthcare provider right away if you take too much Vandetanib.
•During treatment with Vandetanib, your healthcare provider should check your blood and heart for side effects. See “What is the most important information I should know about Vandetanib?”
•Your healthcare provider should check your blood pressure regularly during your treatment with Vandetanib.
What should I avoid while taking Vandetanib?
•Limit exposure to the sun. Vandetanib can make your skin sensitive to the sun. While taking Vandetanib and for 4 months after stopping your Vandetanib treatment, use sun block and wear clothes that cover your skin, including your head, arms and legs when you go outdoors.
•Use caution before driving or using machinery. Keep in mind Vandetanib may make you feel tired, weak, or cause blurred vision.
What are the possible side effects of Vandetanib?
Vandetanib may cause serious side effects, including:
•See “What is the most important information I should know about Vandetanib?”
•Serious skin reactions.
Vandetanib can cause a serious skin reaction, called Stevens-Johnson syndrome or other serious skin reactions that may affect any part of your body. These serious skin reactions may be life threatening and you may need to be treate |
