Duloxetine delayed-release capsules are also used to treat or manage:
Generalized Anxiety Disorder (GAD)
Diabetic Peripheral Neuropathic Pain (DPNP)
Chronic Musculoskeletal Pain
Who should not take duloxetine delayed-release capsules?
Do Not take duloxetine delayed-release capsules if you:
take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid or intravenous methylene blue.
Do not take an MAOI within 5 days of stopping duloxetine delayed-release capsules unless directed to do so by your healthcare provider.
Do not start duloxetine delayed-release capsules if you stopped taking an MAOI in the last 14 days unless directed to do so by your healthcare provider.
People who take duloxetine delayed-release capsules close in time to an MAOI may have a serious problem called Serotonin Syndrome (see "What are the possible side effects of duloxetine delayed-release capsules?").
What should I tell my healthcare provider before taking duloxetine delayed-release capsules?
Before starting duloxetine delayed-release capsules, tell your healthcare provider if you:
have heart problems or high blood pressure
have diabetes (duloxetine delayed-release capsule treatment makes it harder for some people with diabetes to control their blood sugar)
have liver problems
have kidney problems
have glaucoma
have or had seizures or convulsions
have bipolar disorder or mania
have low sodium levels in your blood
have delayed stomach emptying
have or had bleeding problems
are pregnant or plan to become pregnant. It is not known if duloxetine delayed-release capsules will harm your unborn baby. Talk to your healthcare provider about the benefits and risks of treating depression or other conditions with duloxetine delayed-release capsules during pregnancy.
are breastfeeding or plan to breastfeed. Duloxetine can pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking duloxetine delayed-release capsules.
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Duloxetine delayed-release capsules and some medicines may interact with each other, may not work as well, or may cause serious side effects.
Especially tell your healthcare provider if you take:
triptans used to treat migraine headache
medicines used to treat mood, anxiety, psychotic or thought disorders, including tricyclics, lithium, buspirone, SSRIs, SNRIs or MAOIs
tramadol and fentanyl
amphetamines
cimetidine
the antibiotics ciprofloxacin, enoxacin
medicine to treat irregular heart rate (like propafenone, flecainide, quinidine)
theophylline
the blood thinner warfarin (Coumadin*, Jantoven*)
non-steroidal anti-inflammatory drug (NSAID) (like ibuprofen, naproxen or aspirin).
over-the-counter supplements such as tryptophan or St. John's Wort
thioridazine (Mellaril*). Mellaril* together with duloxetine delayed-release capsules can cause serious heart rhythm problems or sudden death.

Ask your healthcare p