VIEKIRA XR(dasabuvir, ombitasvir, paritaprevir, and ritonavir)extended-release tablets(三十六)
provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop taking VIEKIRA XR.
VIEKIRA XR may cause severe liver problems, especially in people with certain types of cirrhosis. These severe liver problems can lead to the need for a liver transplant, or can lead to death.
VIEKIRA XR can cause increases in your liver function blood test results, especially if you use ethinyl estradiol-containing medicines (such as some birth control products).
You must stop using ethinyl estradiol-containing medicines before you start treatment with VIEKIRA XR. See the section “Who should not take VIEKIRA XR?” for a list of these medicines.
If you use these medicines as a method of birth control, you must use another method of birth control during treatment with VIEKIRA XR, and for about 2 weeks after you finish treatment with VIEKIRA XR. Your healthcare provider will tell you when you may begin taking ethinyl estradiol-containing medicines.
Your healthcare provider should do blood tests to check your liver function during the first 4 weeks and then as needed, during treatment with VIEKIRA XR.
Your healthcare provider may tell you to stop taking VIEKIRA XR if you develop signs or symptoms of liver problems.
Tell your healthcare provider right away if you develop any of the following symptoms, or if they worsen during treatment with VIEKIRA XR:
tiredness
weakness
loss of appetite
nausea and vomiting
yellowing of your skin or eyes
color changes in your stools
confusion
swelling of the stomach area
For more information about side effects, see the section “What are the possible side effects of VIEKIRA XR?”
What is VIEKIRA XR?
VIEKIRA XR is a prescription medicine used with or without ribavirin to treat people with genotype 1 chronic (lasting a long time) hepatitis C virus (HCV) infection.
VIEKIRA XR can be used in people who have compensated cirrhosis.
VIEKIRA XR is not for people with advanced cirrhosis (decompensated). If you have cirrhosis, talk to your healthcare provider before taking VIEKIRA XR. VIEKIRA XR is not for people with certain types of liver problems.
It is not known if VIEKIRA XR is safe and effective in children under 18 years of age.
Who should not take VIEKIRA XR?
Do not take VIEKIRA XR if you:
have certain liver problems
take any of the following medicines:
alfuzosin hydrochloride (Uroxatral®)
atorvastatin (Caduet®, Lipitor®, Liptruzet®)
carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®, TEGRETOL-XR®, TERIL®)
cisapride (Propulsid®)
colchicine (Colcrys®) in patients who have certain kidney or liver problems
dronedarone (Multaq®)
efavirenz (Atripla®, Sustiva®)
ergot containing medicines including:
ergotamine tartrate (Cafergot®, Ergomar®, Ergostat®, Medihaler®, Migergot®, Wigraine®, Wigrettes®)
dihydroergotamine mesylate (D.H.E. 45®, Migranal®)
methylergonovine (Ergotrate®, Methergine®)
ethinyl estradiol-containing medicines:
combination birth control pills or patches, such as Lo Loestrin® FE, Norinyl®, Ortho Tri-Cyclen Lo®, Ortho Evra®
hormonal vaginal rings such as NuvaRing®
the hormone replacement therapy medicine, Fem HRT®
everolimus (Afinitor®, Zortress®)
gemfibrozil (Lopid& |
