lthcare provider if you start to take or have any changes in heart or blood pressure medicines.
Vision problems. ALUNBRIG may cause vision problems. Your healthcare provider may stop ALUNBRIG and refer you to an eye specialist if you develop severe vision problems during treatment with ALUNBRIG. Tell your healthcare provider right away if you have any loss of vision or any change in vision, including:
double vision
seeing flashes of light
blurry vision
light hurting your eyes
new or increased floaters
Muscle pain, tenderness, and weakness (myalgia). ALUNBRIG may increase the level of an enzyme in your blood called creatine phosphokinase (CPK), which may be a sign of muscle damage. Your healthcare provider will do blood tests to check your blood levels of CPK during treatment with ALUNBRIG. Tell your healthcare provider right away if you get new or worsening signs and symptoms of muscle problems, including unexplained muscle pain or muscle pain that does not go away, tenderness, or weakness.
Inflammation of the pancreas (pancreatitis). ALUNBRIG may increase enzymes in your blood called amylase and lipase, which may be a sign of pancreatitis. Your healthcare provider will do blood tests to check your pancreatic enzyme blood levels during treatment with ALUNBRIG. Tell your healthcare provider right away if you get new or worsening signs and symptoms of pancreatitis, including upper abdominal pain that may spread to the back and get worse with eating, weight loss, or nausea.
High blood sugar (hyperglycemia). ALUNBRIG may increase your blood sugar levels. Your healthcare provider will do blood tests to check your blood sugar levels before starting and during treatment with ALUNBRIG. Your healthcare provider may need to start or change your blood sugar medicine to control your blood sugar levels. Tell your healthcare provider right away if you get new or worsening signs and symptoms of hyperglycemia, including:
feeling very thirsty
needing to urinate more than usual
feeling very hungry
feeling sick to your stomach
feeling weak or tired
feeling confused
See "WHAT ARE THE POSSIBLE SIDE EFFECTS OF ALUNBRIG?" for information about side effects.
What is ALUNBRIG?
ALUNBRIG is a prescription medicine used to treat people with non-small cell lung cancer (NSCLC):
that has a certain type of abnormal anaplastic lymphoma kinase (ALK) gene, and
that has spread to other parts of your body, and
who have taken the medicine crizotinib, but their NSCLC worsened or they cannot tolerate taking crizotinib.
It is not known if ALUNBRIG is safe and effective in children.
Before you take ALUNBRIG, tell your healthcare provider about all of your medical conditions, including if you:
have lung or breathing problems
have high blood pressure
have a slow heartbeat
have any vision problems
have or have had pancreatitis
have diabetes mellitus or glucose intolerance
are pregnant or plan to become pregnant. ALUNBRIG can harm your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with ALUNBRIG or think you may be pregnant.
Females who are able to become pregnant should use effective non-hormonal birth control during treatment with ALUNBRIG and for at least 4 months after the final dose of ALUNBRIG. Birth control pills (oral contraceptives) and other hormonal forms of birth control may not be effective if used during treatment with ALUNBRIG. Talk to your healthcare provider about birth control choices that are right |
