Mild
hypersalivation / Early / Incidence not known
xerostomia / Early / Incidence not known
nasal dryness / Early / Incidence not known
laryngitis / Delayed / Incidence not known
xerophthalmia / Early / Incidence not known
mydriasis / Early / Incidence not known
abdominal pain / Early / Incidence not known
vomiting / Early / Incidence not known
nausea / Early / Incidence not known
maculopapular rash / Early / Incidence not known
petechiae / Delayed / Incidence not known
urinary urgency / Early / Incidence not known
fever / Early / Incidence not known
injection site reaction / Rapid / Incidence not known
syncope / Early / Incidence not known
urticaria / Rapid / Incidence not known
leukocytosis / Delayed / Incidence not known
flushing / Rapid / Incidence not known
weakness / Early / Incidence not known
drowsiness / Early / Incidence not known
restlessness / Early / Incidence not known
headache / Early / Incidence not known
paranoia / Early / Incidence not known
anxiety / Delayed / Incidence not known
agitation / Early / Incidence not known
dizziness / Early / Incidence not known
insomnia / Early / Incidence not known
vertigo / Early / Incidence not known

 DRUG INTERACTIONS
Abatacept: Because abatacept has been shown to potentiate the onset of respiratory infections, concomitant use of drugs that decrease mucociliary clearance should be used cautiously. Anticholinergics, such as atropine, have been shown to be capable of depressing the mucociliary transport system.
Acetaminophen; Butalbital; Caffeine; Codeine: Opiate agonists should be used cautiously with antimuscarinics since additive depressive effects on GI motility or bladder function may been seen. Opioids increase the tone and decrease the propulsive contractions of the smooth muscle of the gastrointestinal tract. Prolongation of the gastrointestinal transit time may be the mechanism of the constipating effect. Opiate analgesics combined with antimuscarinics can cause severe constipation or paralytic ileus, especially with chronic use. Pharmacology texts report that meperidine exerts less pronounced effects on GI smooth muscle than other opiate agonists.
Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine: The anticholinergic effects of sedating H1-blockers may be enhanced when combined with other antimuscarinics. Clinicians should note that anticholinergic effects mi