Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

VICTRELIS and other medicines may affect each other, causing side effects or affecting the way VICTRELIS and your other medicines work. Do not start taking a new medicine without telling your healthcare provider or pharmacist.

Do not take VICTRELIS if you take:

• alfuzosin hydrochloride (UROXATRAL®)
• anti-seizure medicines:
  • carbamazepine (CARBATROL®, EPITOL®, EQUETRO®, TEGRETOL®, TEGRETOL® XR, TERIL™)
  • phenobarbital
  • phenytoin (DILANTIN®)
• cisapride (PROPULSID®)
• drosperinone-containing medicines, including:
  • YAZ®, YASMIN®, ZARAH®, OCELLA®, GIANVI®, BEYAZ®, SAFYRAL™
• ergot-containing medicines, including:
  • dihydroergotamine mesylate (D.H.E. 45®, MIGRANAL®)
  • ergonovine and methylergonovine (ERGOTRATE®, METHERGINE®), ergotamine
  • ergotamine tartrate (CAFERGOT®, MIGERGOT®, ERGOMAR®, ERGOSTAT, MEDIHALER ERGOTAMINE, WIGRAINE, WIGRETTES)
• lovastatin (ADVICOR®, ALTOPREV®, MEVACOR®)
• midazolam (VERSED), when taken by mouth
• pimozide (ORAP®)
• rifampin (RIFADIN®, RIFAMATE®, RIFATER®, RIMACTANE)
• sildenafil (REVATIO®), when used for treating lung problems
• simvastatin (SIMCOR®, VYTORIN®, ZOCOR®)
• St. John's Wort (Hypericum perforatum) or products containing St. John's Wort
• tadalafil (ADCIRCA®), when used for treating lung problems
• triazolam (HALCION®)

Tell your healthcare provider if you are taking or starting to take any of these medicines:

• clarithromycin (BIAXIN®, BIAXIN® XL, PREVPAC®)
• dexamethasone
• efavirenz (SUSTIVA®, ATRIPLA®)
• itraconazole (SPORANOX®)
• ketoconazole (NIZORAL®)
• posaconazole (NOXAFIL®)
• rifabutin (MYCOBUTIN®)
• ritonavir (NORVIR®, KALETRA®)
• voriconazole (VFEND®)

Your healthcare provider may need to monitor your therapy more closely if you take VICTRELIS with the following medicines. Talk to your doctor if you are taking or starting to take these medicines: