|
ately 4% of hairy cell leukemia patients, in each arm, died more than 60 days after the last dose of either treatment and there was no outstanding cause of death among these patients.
|
All Adverse
Events a
|
Percent of Patients |
Frontline, Treated With
NIPENT
N=180 |
Frontline, Treated With
IFN
N=176 |
IFN-Refractory Treated With
NIPENT
N=197 |
|
Nausea and/or
Vomiting
|
63 |
22 |
53 b |
|
Fever
|
46 |
59 |
42 |
|
Rash
|
43 |
30 |
26 |
|
Fatigue
|
42 |
55 |
29 |
|
Leukopenia
|
22 |
15 |
60 |
|
Pruritus
|
21 |
6 |
10 |
|
Coughing/Increased
Cough
|
20 |
15 |
17 |
|
Myalgia
|
19 |
36 |
11 |
|
Chills
|
19 |
34 |
11 |
|
Headache
|
17 |
29 |
13 |
|
Diarrhea
|
17 |
17 |
15 |
|
Abdominal Pain
|
16 |
15 |
4 |
|
Anorexia
|
13 |
10 |
16 |
|
Upper Respiratory
Infection
|
13 |
8 |
16 |
|
Asthenia
|
12 |
13 |
10 |
|
Stomatitis
|
12 |
7 |
5 |
|
Rhinitis
|
11 |
15 |
10 |
|
Dyspnea
|
11 |
13 |
8 |
|
Anemia
|
8 |
5 |
35 |
|
Pain
|
8 |
19 |
20 |
|
Pharyngitis
|
8 |
11 |
10 |
|
Sweating Increased/
Sweating
|
8 |
21 |
10 |
|
Viral Infection
|
8 |
17 |
NR |
|
Infection
|
7 c |
2 c |
36 |
|
Arthralgia
|
6 |
14 |
3 |
|
Thrombocytopenia
|
6 |
6 |
32 |
|
Skin Disorder
|
4 |
5 |
17 |
|
Allergic Reaction
|
2 |
1 |
11 |
|
Hepatic Disorder/
Elevated Liver
Function Tests d
|
2 |
2 |
|
|
