|
Tegretol Tablets 100mg, 200mg, 400mg(十二)
, memory impairment
Eye disorders
Common:
accommodation disorders (e.g. blurred vision)
Very rare:
lenticular opacities, conjunctivitis.
Ear and labyrinth disorders
Very rare:
hearing disorders, e.g. tinnitus, hyperacusis, hypoacusis, change in pitch perception.
Cardiac disorders
Rare:
cardiac conduction disorders.
Very rare:
arrhythmia, atrioventricular block with syncope, bradycardia, cardiac failure congestive, coronary artery disease aggravated.
Vascular disorders
Rare:
hypertension or hypotension.
Very Rare:
circulatory collapse, embolism (e.g. pulmonary embolism), thrombophlebitis.
Respiratory, thoracic and mediastinal disorders
Very rare:
pulmonary hypersensitivity characterised e.g. by fever, dyspnoea, pneumonitis or pneumonia.
Gastro-intestinal disorders
Very common:
vomiting, nausea.
Common:
dry mouth, with suppositories rectal irritation may occur.
Uncommon:
diarrhoea, constipation.
Rare:
abdominal pain.
Very rare:
Pancreatitis, glossitis, stomatitis,.
Not known**:
colitis.
Hepatobiliary disorders
Rare:
hepatitis of cholestatic, parenchymal (hepatocellular) or mixed type, vanishing bile duct syndrome, jaundice.
Very rare:
hepatic failure, granulomatous liver disease.
Skin and subcutaneous tissue disorders:
Very common:
urticaria, which may be severe dermatitus allergic,
Uncommon:
dermatitis exfoliative.
Rare:
systemic lupus erythematosus, pruritus.
Very rare:
Stevens-Johnson syndrome*, toxic epidermal necrolysis, photosensitivity reaction, erythema multiforme, erythema nodosum, pigmentation disorder, purpura, acne, hyperhydrosis, alopecia, hirsutism.
Not known**:
Acute Generalized Exanthematous Pustulosis (AGEP)**, lichenoid keratosis, onychomadesis.
Musculoskeletal, connective tissue and bone disorders
Rare:
muscular weakness.
Very rare:
bone metabolism disorders (decrease in plasma calcium and blood 25-hydroxy-cholecalciferol) leading to osteomalacia/osteoporosis, arthralgia, myalgia, muscle spasms.
Not known**:
fracture.
Renal and urinary disorders
Very rare:
tubulointerstitial nephritis, renal failure, renal impairment (e.g. albuminuria, haematuria, oliguria and blood urea/ azotaemia), urinary retention, urinary frequency.
Reproductive System
Very rare:
sexual disturbances/erecticle dysfunction spermatogenesis abnormal (with decreased sperm count and/or motility).
General disorders and administration site conditions
Very common:
fatigue.
Investigations
Very common:
gamma-glutamyltransferase increased (due to hepatic enzyme induction), usually not clinically relevant.
|
|
