to treat:
moderately to severely active rheumatoid arthritis (RA). ENBREL® can be used alone or with a medicine called methotrexate.
psoriatic arthritis. ENBREL® can be used alone or with methotrexate.
ankylosing spondylitis (AS)
chronic, moderate to severe plaque psoriasis in adults ages 18 years and older
moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.
You may continue to use other medicines that help treat your condition while taking ENBREL®, such as non-steroidal anti-inflammatory drugs (NSAIDs) and prescription steroids, as recommended by your doctor.
ENBREL® can help reduce joint damage, and the signs and symptoms of the above mentioned diseases. People with these diseases have too much of a protein called tumor necrosis factor (TNF), which is made by your immune system. ENBREL® can reduce the effect of TNF in the body and block the damage that too much TNF can cause, but it can also lower the ability of your immune system to fight infections. See “What is the most important information I should know about ENBREL® ?” and “What are the possible side effects of ENBREL® ?”
Who should not use ENBREL®?
Do not use ENBREL® if you:
have an infection that has spread through your body (sepsis)
have ever had an allergic reaction to ENBREL®. See the end of this Medication Guide for a complete list of ingredients in ENBREL®.
How should I use ENBREL®?
ENBREL® is given as an injection under the skin (subcutaneous or SC).
If your doctor decides that you or a caregiver can give the injections of ENBREL® at home, you or your caregiver should receive training on the right way to prepare and inject ENBREL®. Do not try to inject ENBREL® until you have been shown the right way by your doctor or nurse.
ENBREL® is available in the forms listed below. Your doctor will prescribe the type that is best for you.
Single-use Prefilled Syringe
Single-use Prefilled SureClick Autoinjector
Multiple-use Vial
See the detailed “Patient Instructions for Use” with this Medication Guide for instructions about the right way to prepare and give your ENBREL® injections at home.
Your doctor will tell you how often you should use ENBREL®. Do not miss any doses of ENBREL®. If you forget to use ENBREL®, inject your dose as soon as you remember. Then, take your next dose at your regular(ly) scheduled time. In case you are not sure when to inject ENBREL®, call your doctor or pharmacist. Do not use ENBREL® more often than as directed by your doctor.
Your child’s dose of ENBREL® depends on his or her weight. Your child’s doctor will tell you which form of ENBREL® to use and how much to give your child.
What are the possible side effects of ENBREL®?
ENBREL® can cause serious side effects, including:
See “What is the most important information I should know about ENBREL® ?”
Infections. ENBREL® can make you more likely to get infections or make any infection that you have worse. Call your doctor right away if you have any symptoms of an infection. See “Before starting ENBREL®, be sure to talk to your doctor” for a list of symptoms of infection.
Hepatitis B infection in people who carry the virus in their blood. If you are a carrier of the hepatitis B virus (a virus that affects the liver), the virus can become active whil |
