sed dose. If you are not sure about what to do, call your healthcare provider.
• You should have blood tests before you start AFINITOR or AFINITOR DISPERZ and as needed during your treatment. These will include tests to check your blood cell count, kidney and liver function, cholesterol, and blood sugar levels.
• If you take AFINITOR or AFINITOR DISPERZ to treat SEGA, you will also need to have blood tests regularly to measure how much medicine is in your blood. This will help your healthcare provider decide how much AFINITOR or AFINITOR DISPERZ you need to take.
What should I avoid while taking AFINITOR or AFINITOR DISPERZ?
You should not drink grapefruit juice or eat grapefruit during your treatment with AFINITOR or AFINITOR DISPERZ. It may make the amount of AFINITOR in your blood increase to a harmful level.
What are the possible side effects of AFINITOR or AFINITOR DISPERZ?
AFINITOR and AFINITOR DISPERZ can cause serious side effects.
•See “What is the most important information I should know about AFINITOR and AFINITOR DISPERZ?” for more information.
•Delayed wound healing. AFINITOR can cause incisions to heal slowly or not heal well. Call your healthcare provider right away if you have any of the following symptoms:
◦your incision is red, warm or painful
◦blood, fluid, or pus in your incision
◦your incision opens up
◦swelling of your incision
Common side effects of AFINITOR in people with advanced hormone receptor-positive, HER 2-negative breast cancer, advanced pancreatic neuroendocrine tumors, and advanced kidney cancer include:
•Mouth ulcers. AFINITOR can cause mouth ulcers and sores. Tell your healthcare provider if you have pain, discomfort, or open sores in your mouth. Your healthcare provider may tell you to use a special mouthwash or mouth gel that does not contain alcohol, peroxide, iodine, or thyme.
•Infections
•Feeling weak or tired
•Cough, shortness of breath
•Diarrhea and constipation
•Rash, dry skin, and itching
•Nausea and vomiting
•Fever
•Loss of appetite, weight loss
•Swelling of arms, hands, feet, ankles, face or other parts of the body
•Abnormal taste
•Dry mouth
•Inflammation of lining of the digestive system
•Headache
•Nose bleeds
•Pain in arms and legs, mouth and throat, back or joints
•High blood glucose
•High blood pressure
•Difficulty sleeping
•Hair loss
•Muscle spasms
•Feeling dizzy
•Nail disorders
Common side effects of AFINITOR and AFINITOR DISPERZ in people who have SEGA or renal angiomyolipoma with TSC include:
•Mouth ulcers. AFINITOR can cause mouth ulcers and sores. Tell your healthcare provider if you have pain, discomfort, or open sores in your mouth. Your healthcare provider may tell you to use a special mouthwash or mouth gel that does not contain alcohol, peroxide, iodine, or thyme.
•Infections
•Nausea and vomiting
•Diarrhea and constipation
•Swelling of your hands, arms, legs, and feet
•Joint pain
•Cough
•Skin problems (such as rash, acne, or dry skin)
•Fever
•Feeling tired
•Anxiety, aggression, and other abnormal behaviors
•Absence of menstrual periods (menstruation). You may miss 1 or more menstrual periods. Tell you |
