y be severe and can even lead to death. Your healthcare provider should do tests to check your kidney function before and during your treatment with AFINITOR or AFINITOR DISPERZ.
If you have any of the serious side effects listed above, you may need to stop taking AFINITOR or AFINITOR DISPERZ for a while or use a lower dose. Follow your healthcare provider’s instructions.
What is AFINITOR?
AFINITOR is a prescription medicine used to treat:
◦advanced hormone receptor-positive, HER2-negative breast cancer, along with the medicine exemestane, in postmenopausal women who have already received certain other medicines for their cancer.
◦adults with a type of pancreatic cancer known as pancreatic neuroendocrine tumor (PNET), that has progressed and cannot be treated with surgery.
AFINITOR is not for use in people with carcinoid tumors that actively produce hormones.
◦adults with advanced kidney cancer (renal cell carcinoma or RCC) when certain other medicines have not worked.
◦people with the following types of tumors that are seen with a genetic condition called tuberous sclerosis complex (TSC):
◦adults with a kidney tumor called angiomyolipoma, when their kidney tumor does not require surgery right away.
◦adults and children with a brain tumor called subependymal giant cell astrocytoma (SEGA) when the tumor cannot be removed completely by surgery.
What is AFINITOR DISPERZ?
AFINITOR DISPERZ is a prescription medicine used to treat:
◦adults and children with a genetic condition called tuberous sclerosis complex (TSC) who have a brain tumor called subependymal giant cell astrocytoma (SEGA) when the tumor cannot be removed completely by surgery.
Who should not take AFINITOR or AFINITOR DISPERZ?
Do not take AFINITOR or AFINITOR DISPERZ if you are allergic to everolimus or to any of the ingredients in AFINITOR or AFINITOR DISPERZ. See the end of this leaflet for a complete list of ingredients in AFINITOR and AFINITOR DISPERZ.
Talk to your healthcare provider before taking this medicine if you are allergic to:
•sirolimus (Rapamune®)
•temsirolimus (Torisel®)
Ask your healthcare provider if you do not know.
What should I tell my healthcare provider before taking AFINITOR or AFINITOR DISPERZ?
Before taking AFINITOR or AFINITOR DISPERZ, tell your healthcare provider about all of your medical conditions, including if you:
•Have or have had kidney problems
•Have or have had liver problems
•Have diabetes or high blood sugar
•Have high blood cholesterol levels
•Have any infections
•Previously had hepatitis B
•Are scheduled to receive any vaccinations. You should not receive a “live vaccine” or be around people who have recently received a “live vaccine” during your treatment with AFINITOR or AFINITOR DISPERZ. If you are not sure about the type of immunization or vaccine, ask your healthcare provider.
•Are pregnant, or could become pregnant. AFINITOR or AFINITOR DISPERZ can cause harm to your unborn baby. You should use effective birth control while using AFINITOR or AFINITOR DISPERZ and for 8 weeks after stopping treatment. Talk to your healthcare provider about birth control options while taking AFINITOR or AFINITOR DISPERZ.
•Are breastfeeding or plan to breastfeed. It is not known if AFINITOR or AFINITOR DISPERZ passes into your breast milk. You |
