HYQVIA [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase](二十三)
re the Hyaluronidase (Labeled as “HY”):
•
Prior to use, take off the protective caps and wipe each of the HY vials (top of vial) with an alcohol wipe and allow to dry
•
Remove sterile syringe from package and attach to a sterile needle/needle-less transfer device. Due to the small stopper diameter; use an 18 – 22 gauge sterile needle for the HY 1.25 vial. A sterile needle or needle-less transfer device may be used for all other vial sizes.
•
Pull back on plunger of the syringe to fill the syringe with air equal to the amount in the HY vial.
•
Position the sharp tip of the needle/needle-less transfer device over the center of the vial stopper and insert it at a 90-degree angle.
•
Inject air into the vial and withdraw the full contents of the HY vial(s) into a syringe,
•
Repeat the above steps for each additional HY vial using the same syringe, if possible.
•
Remove the syringe from the needle/needle-less transfer device.
•
Attach the syringe filled with HY to the needle set
•
Point the syringe tip up and push the plunger of the syringe to remove the air and fill the needle set up to the needle hub with the HY.
1.
Prepare the immune globulin (Labeled as “IG”):
•
Wipe each stopper with a sterile alcohol wipe and allow to dry.
•
Transfer the vial(s) labeled IG into either syringe(s) or an infusion bag or as shown by your healthcare professional:
o
If using syringe(s)
Attach a sterile syringe to a vented spike.
Insert the vented spike into the center of the IG vials.
Turn the vial upside down and pull back on the plunger to pull the IG into the syringe(s).
Repeat these steps, if using multiple vials to achieve the desired dose.
If using a sterile needle, attach a sterile syringe to the sterile needle and pull back the plunger of syringe to fill with air which should equal amount of the liquid you will be taking from the vial. Insert the needle into the center of the stopper, and inject air in. Pull back on the plunger to withdraw the desired volume.
o
If using an infusion bag:
Insert the vented spike into the center of each IG vial. Open the vent.
Turn the vial upside down and fill the bag with the IG. Repeat this step, if using multiple vials to achieve the desired dose.
Remove the filling tube(s) of the bag and place a sterile cap over the open end of the bag and close the clamp on bag.
Insert the spike of the administration pump tubing into the bag and fill as directed by your healthcare professional.
1.
Prepare the infusion site:
•
Choose an infusion site(s) in either the middle or upper abdomen or thigh. Avoid: bony areas, visible blood vessels, scars and any areas of inflammation (irritation) or infection.
•
Select sites on the opposite sides of the body if instructed to infuse in two sites.
•
Rotate sites by choosing opposite sides of the body between future infusions.
•
Wipe the infusion site(s) with a sterile alcohol wipe beginning at the center of each infusion site and moving outward in a circular motion. Allow the infusion site(s) to dry (at least 30 seconds).
1.
Insert and secure the 24 gauge subcutaneous needle:
•
Remove the needle cover. Firmly grasp and pinch at least 1 inch of skin between two fingers.
•
Insert needle with |
