If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

The safety of this medicine for use during pregnancy has not been established. It should therefore be used with caution during pregnancy, and only if the benefits to the mother outweigh any potential risks to the developing baby. Seek medical advice from your doctor.
It is not known whether this medicine passes into breast milk. Mothers who need treatment with this medicine should not breastfeed. Seek medical advice from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

Headache.
Disturbances of the gut such as nausea, vomiting, diarrhoea, constipation, indigestion or abdominal pain.
Pain, redness or itching at the infusion site.
Rash.
Fungal infections, such as thrush.
Elevated levels of liver enzymes and creatine phosphokinase (CPK).
Urinary tract infection.
Blood disorders such as anaemia, thrombocythaemia.
Loss of appetite.
Anxiety.
Difficulty sleeping (insomnia).
Pins and needles (paraesthesia, see also warning above).
Dizziness.
Alteration in taste.
Fatigue, weakness or loss of strength (asthenia).
Changes in heart rhythm or blood pressure.
Jaundice.
Muscle pain, inflammation, weakness (see warning above).
Kidney problems.
Joint pain (arthralgia).
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while being treated with this one, to ensure that the combination is safe.

There may be an increased risk of side effects on the muscles (myopathy) if daptomycin is used in combination with any of the following medicines:

ciclosporin
fibrates for lowering cholesterol, eg bezafibrate, gemfibrozil
statins for lowering cholesterol, eg simvastatin, rosuvastatin.
The manufacturer recommends that, if possible, the medicines above should be temporarily stopped during treatment with daptomyc