Antidepressant medicines have other side effects. Talk to the healthcare provider about the side effects of the medicine prescribed for you or your family member.

Antidepressant medicines can interact with other medicines. Know all of the medicines that you or your family member takes. Keep a list of all medicines to show the healthcare provider. Do not start new medicines without first checking with your healthcare provider.

Not all antidepressant medicines prescribed for children are FDA approved for use in children. Talk to your child’s healthcare provider for more information.

What is SEROQUEL XR?

SEROQUEL XR is a prescription medicine used to treat schizophrenia in adults.

SEROQUEL XR is a prescription medicine used to treat bipolar disorder in adults, including:

manic episodes associated with bipolar disorder alone or with lithium or divalproex.

depressive episodes associated with bipolar disorder.

long-term treatment of bipolar I disorder with lithium or divalproex.

SEROQUEL XR is a prescription medicine used to treat major depressive disorder as add-on treatment with antidepressant medicines when your doctor determines that one antidepressant alone is not enough to treat your depression.

SEROQUEL XR is not approved for patients under 18 years of age.

What should I tell my healthcare provider before taking SEROQUEL XR?

Before taking SEROQUEL XR, tell your healthcare provider if you have or have had:

diabetes or high blood sugar in you or your family: your healthcare provider should check your blood sugar before you start SEROQUEL XR and also during therapy.

high levels of total cholesterol, triglycerides or LDL-cholesterol or low levels of HDL- cholesterol

low or high blood pressure

low white blood cell count

cataracts

seizures

abnormal thyroid tests

high prolactin levels

heart problems

liver problems

any other medical condition

pregnancy or plans to become pregnant. It is not known if SEROQUEL XR will harm your unborn baby.

breast-feeding or plans to breast-feed. It is not known if SEROQUEL XR will pass into your breast milk. You and your healthcare provider should decide if you will take SEROQUEL XR or breast-feed. You should not do both.

Tell the healthcare provider about all the medicines that you take or recently have taken including prescription medicines, non-prescription medicines, herbal supplements and vitamins.

SEROQUEL XR and other medicines may affect each other causing serious side effects. SEROQUEL XR may affect the way other medicines work, and other medicines may affect how SEROQUEL XR works.

Especially tell your healthcare provider if you take or plan to take medicines for:

depression

high blood pressure

Parkinson's disease

trouble sleeping

Also tell your healthcare provider if you take or plan to take any of these medicines:

phenytoin, divalproex or carbamazepine (for epilepsy)

barbiturates (to help you sleep)

rifampin (for tuberculosis)

glucocorticoids (steroids for inflammation)

thioridazine (an antipsychotic)

ketoconazole, fluconazole or itraconazole (for fungal infections)

erythromycin (an antibiotic)

protease inhibitors (