DO NOT use hot tubs, whirlpools, or saunas while wearing the On-body Injector. This may affect your medicine.

DO NOT expose the On-body Injector to direct sunlight. If the On-body Injector is exposed to direct sunlight for more than 1 hour, it may affect your medicine. Wear the On-body Injector under clothing.

DO NOT sleep on the On-body Injector or apply pressure during wear, especially during dose delivery. This may affect the On-body Injector performance.

DO NOT peel off or disturb the On-body Injector’s adhesive before your full dose is complete. This may result in a missed or incomplete dose of Neulasta.
 
Precautions

Environmental:

Keep the On-body Injector dry for the last 3 hours prior to the dose delivery start.

Only expose the On-body Injector to temperatures between 41°F and 104°F (5°C-40°C).

Keep the On-body Injector at least 4 inches away from electrical equipment such as cell phones, cordless telephones, microwaves and other common appliances. Failure to keep the On-body Injector at least this recommended distance may interfere with operation and can lead to a missed or incomplete dose of Neulasta.
Activity Related:

Avoid getting body lotions, creams, oils or cleaning agents near the On-body Injector as these products may loosen the adhesive.

Be careful not to bump the On-body Injector or knock the On-body Injector off your body.
Biohazard:

Properly dispose of the On-body Injector:

The On-body Injector contains batteries, electronics, and a needle. The On-body Injector should be placed in a sharps disposal container, with an appropriate sized opening, regardless of whether or not the needle is exposed. Follow instructions provided by your healthcare provider or by state or local laws.

To participate in Amgen’s voluntary disposal program, please call 1-844-MYNEULASTA (1-844-696-3852) or visit www.neulasta.com to enroll.

For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to FDA’s website at: http://www.fda.gov/safesharpsdisposal.
Risks

You can avoid most risks related to using the On-body Injector for Neulasta by following the Patient Instructions for Use. Immediately call your healthcare provider if any of the following occur:

The adhesive becomes noticeably wet (saturated) with fluid, or you see dripping

If the On-body Injector fill indicator is not at the empty position after On-body Injector removal (You should see a black line next to the EMPTY indicator.)

The On-body Injector comes off from the skin before or during a dose delivery (DO NOT re-apply it.)

Status light is flashing red

Allergic reaction

Persistent or worsening redness or tenderness at the application site (may be a sign of infection)

Severe pain or skin discomfort around your On-body Injector

Any concern about your medication

If the needle is exposed after On-body Injector removal
INSTRUCTIONS FOR USE
On-body Injector for Neulasta® (nu-las-tah) (pegfilgrastim) Injection
Patient Instructions for Use
Important Information
 This On-body Injector delivers Neulasta with an under-the-skin (subcutaneous) injection. See Patient Information for medi