D Beeping will tell you the cannula is about to insert. You may hear a series of clicks. This is okay.
A long beep will sound, and the status light will turn to green. This means the cannula insertion is complete.
 
 If the adhesive folds over near the cannula window or there are folds anywhere that prevent the On-body Injector from securely adhering, remove the On-body Injector.
Start again with a new Neulasta Onpro kit and call Amgen at 1-800-772-6436.
Step 4: Finish
A Fill in the Dose Delivery Information section in the patient instructions.  
Be sure to include when the On-body Injector was applied, when the dose will begin, and your contact information. Review this information with the patient.
Review each step in the patient instructions with your patient. Give your patient the instructions, and reference guide to take home.
Before your patient goes home, make sure your patient understands:
 ● The On-body Injector will always flash a slow green light to let them know it is working properly.
 ● After approximately 27 hours, beeps will signal that the dose delivery will begin in 2 minutes.
 ● When the dose delivery starts it will take about 45 minutes to complete. During this time, the On-body Injector will flash a fast green light.
 ● The patient should remain in a place where they can monitor the On-body Injector for the entire dose delivery.  The patient should avoid activities and settings that may interfere with monitoring during the dosing of Neulasta administered by the On-body Injector. For example, avoid traveling, driving, or operating heavy machinery during hours 26-29 following application of the On-body Injector (this includes the approximately 45-minute delivery period plus an hour post-delivery). 
 ● If the patient has an allergic reaction during the delivery of Neulasta, the patient should remove the On-body Injector and call his or her healthcare provider or seek emergency care right away.
 ● If placed on the back of the arm, remind the patient that a caregiver must be available to monitor the On-body Injector. 
 ● When the dose delivery is complete, the patient or caregiver will hear a beep and see a solid green light.
 ● Always dispose of the empty On-body Injector in a sharps disposal container as instructed by your healthcare provider or by state or local laws.
 ● Keep the On-body Injector at least 4 inches away from electrical equipment such as cell phones, cordless telephones, microwaves and other common appliances. Failure to keep the On-body Injector at least this recommended distance may interfere with operation and can lead to a missed or incomplete dose of Neulasta.
 
 If at any time the On-body Injector beeps continuous