trouble breathing

swelling of your stomach-area (abdomen) and feeling of fullness

dizziness or feeling faint

a general feeling of tiredness
What are the most common side effects of Neulasta?

The most common side effect you may experience is aching in the bones and muscles. If this happens, it can usually be relieved with a non-aspirin pain reliever, such as acetaminophen.

What about pregnancy or breastfeeding?

Neulasta has not been studied in pregnant women, and its effects on unborn babies are not known. If you take Neulasta while you are pregnant, it is possible that small amounts of it may get into your baby’s blood. It is not known if Neulasta can get into human breast milk. If you are pregnant, plan to become pregnant, think you may be pregnant, or are breastfeeding, you should tell your doctor before using Neulasta. If you become pregnant during Neulasta treatment, you are encouraged to enroll in Amgen’s Pregnancy Surveillance Program. You should call
1-800-77-AMGEN (1-800-772-6436) to enroll.

HOW TO PREPARE AND GIVE A NEULASTA INJECTION

If your child weighs less than 45 kg, do not use the prefilled syringe for direct administration of Neulasta. The Neulasta prefilled syringe is not designed to allow for direct administration of doses less than 6 mg.

Neulasta is provided in a prefilled syringe. Neulasta should be stored in its carton to protect from light until use. If you are giving someone else Neulasta injections, it is important that you know how to inject Neulasta. Before getting your Neulasta injection, always check to see that:

The name Neulasta appears on the carton and prefilled syringe label.

The expiration date on the prefilled syringe has not passed. You should not use a prefilled syringe after the date on the label.

The Neulasta liquid should always be clear and colorless. Do not use Neulasta if the contents of the prefilled syringe appear discolored or cloudy, or if the prefilled syringe appears to contain lumps, flakes, or particles.
IMPORTANT: TO HELP AVOID POSSIBLE INFECTION, YOU SHOULD FOLLOW THESE INSTRUCTIONS.

Setting up for an injection

Note: The needle cover on the single-use prefilled syringe contains dry natural rubber (latex), which should not be handled by persons sensitive to this substance.

1.Find a clean, flat working surface, such as a table.

2.Remove the carton containing the prefilled syringe of Neulasta from the refrigerator. Allow Neulasta to reach room temperature (this takes about 30 minutes). Remove the syringe from the carton before injection. Each prefilled syringe should be used only once. DO NOT SHAKE THE PREFILLED SYRINGE. Shaking may damage Neulasta. If the prefilled syringe has been shaken vigorously, the solution may appear foamy and it should not be used.

3.Assemble the supplies you will need for an injection:
Neulasta prefilled syringe with transparent (clear) plastic blue needle guard attached

An alcohol swab and a cotton ball or gauze           

Puncture-proof disposal container
4. Wash your hands with soap and warm water.

HOW TO PREPARE FOR INJECTION OF NEULASTA

5. Remove the prefilled syringe from the package and the tray. Check to see that the plastic blue