bull;Drink at least eight 8-ounce glasses of liquids every day while taking ZOLINZA. Drinking enough fluids may help to decrease the chances of losing too much fluid from your body (dehydration) especially if you are having symptoms such as nausea, vomiting or diarrhea while taking ZOLINZA.
•If you miss a dose, take it as soon as you remember. If you do not remember until it is almost time for your next dose, just skip the missed dose. Just take the next dose at your regular time. Do not take two doses of ZOLINZA at the same time.
•If you take too much ZOLINZA, call your doctor, local emergency room, or poison control center right away.
•Your doctor will check your blood cell counts, blood sugar, blood electrolytes, and other chemistries every two weeks for the first two months of your treatment with ZOLINZA and then monthly. Your doctor may decide to do other tests to check your health as needed.
•If you have high blood sugar (hyperglycemia) or diabetes, continue to monitor your blood sugar as your doctor tells you to. Your doctor may need to change your diet or medicine to help control your blood sugar while you take ZOLINZA. Be sure to tell your doctor if you are unable to eat or drink normally due to nausea, vomiting or diarrhea.
What are the possible side effects of ZOLINZA?
ZOLINZA may cause serious side effects. Tell your doctor right away if you have any of the following symptoms:
•Blood clots in the legs (deep vein thrombosis)
◦sudden swelling in a leg
◦pain or tenderness in the leg. The pain may only be felt when standing or walking.
◦increased warmth in the area where the swelling is.
◦skin redness or change in skin color
•Blood clots that travel to the lungs (pulmonary embolus) •sudden sharp chest pain
•shortness of breath
•cough with bloody secretions
•sweating
•rapid pulse
•fainting
•feeling anxious
•Dehydration (loss of too much fluid from the body). This can happen if you are having nausea, vomiting or diarrhea and can not drink fluids well.
•Changes in blood tests: Your doctor will periodically do blood tests to check your blood counts and electrolytes.
◦Low red blood cells. Low red blood cells may make you feel tired and get tired easily. You may look pale, and feel short of breath.
◦Low platelets. Low platelets can cause unusual bleeding or bruising under the skin. Talk to your doctor right away if this happens.
•High blood sugar (blood glucose). If you have high blood sugar or diabetes, monitor your blood sugar frequently as directed by your doctor. Tell your doctor right away if your blood sugar is higher than normal.
In addition, the most common side effects with ZOLINZA include:
•Stomach and intestinal problems, including diarrhea, nausea, vomiting, loss of appetite, constipation and weight loss
•Tiredness
•Dizziness
•Headache
•Changes in the way things taste and dry mouth
•Muscle aches
•Hair loss
•Chills
•Fever
•Upper respiratory infection
•Cough
•Increase in blood creatinine
•Swelling in the foot, ankle, and leg
•Itching
Tell your doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of ZOLINZA. For more information, ask your doctor or pharmacist.
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