3.
Do not take INCIVEK alone to treat chronic hepatitis C infection. INCIVEK must be used with peginterferon alfa and ribavirin to treat chronic hepatitis C infection.
What is INCIVEK?

INCIVEK is a prescription medicine used with the medicines peginterferon alfa and ribavirin to treat chronic (lasting a long time) hepatitis C genotype 1 infection in adults with stable liver problems, who have not been treated before or who have failed previous treatment.

It is not known if INCIVEK is safe and effective in children under 18 years of age.

Who should not take INCIVEK?

Do not take INCIVEK if you:

are pregnant or may become pregnant. See "What is the most important information I should know about INCIVEK?"
are a man with a sexual partner who is pregnant.
take certain medicines. INCIVEK may cause serious side effects when taken with certain medicines. Read the section "What should I tell my healthcare provider before taking INCIVEK?"
Talk to your health care provider before taking INCIVEK if any of the above applies to you.

What should I tell my healthcare provider before taking INCIVEK?

Before you take INCIVEK, tell your healthcare provider if you:

have certain blood problems, such as low red blood cell count (anemia)
have liver problems other than hepatitis C infection
have hepatitis B infection
have Human Immunodeficiency Virus (HIV) infection or any other problems with your immune system
history of gout or high uric acid levels in your blood
have had an organ transplant
plan to have surgery
have any other medical condition
are breastfeeding. It is not known if INCIVEK passes into your breast milk. You and your healthcare provider should decide if you will take INCIVEK or breastfeed. You should not do both.
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

INCIVEK and other medicines can affect each other. This can cause you to have too much or not enough INCIVEK or your other medicines in your body, and cause side effects that can be serious or life-threatening. Your healthcare provider may need to change the amount of medicine you take.

Do not take INCIVEK if you take:

alfuzosin hydrochloride (Uroxatral®)
atorvastatin (Lipitor®, Caduet®)
ergot containing medicines such as methylergonovine (Methergine®)
lovastatin (Advicor®, Altoprev®, Mevacor®)
pimozide (Orap®)
rifampin (Rifadin®, Rifamate®, Rifater®)
sildenafil citrate (Revatio®) or tadalafil (Adcirca®) for the lung problem, pulmonary artery hypertension (PAH)
simvastatin (Zocor®, Vytorin®, Simcor®)
St. John's wort (Hypericum perforatum) or products containing St. John's wort
triazolam (Halcion®)
Know the medicines you take. Keep a list of them with you and show it to your healthcare provider and pharmacist each time you get a new medicine.

How should I take INCIVEK?

Take INCIVEK exactly as your healthcare provider tells you. Your healthcare provider will tell you how much INCIVEK to take and when to take it.
Take INCIVEK 3 times a day. Each dose should be taken 7 to 9 hours apart. Eat a mea