Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist before you start a new medicine.

OSENI may affect the way other medicines work, and other medicines may affect how OSENI works. Contact your doctor before you start or stop other types of medicines.

How should I take OSENI?

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Take OSENI exactly as your doctor tells you to take it.
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Take OSENI 1 time each day with or without food.
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Do not break or cut OSENI tablets before swallowing.
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Your doctor may need to change your dose of OSENI to control your blood glucose. Do not change your dose unless told to do so by your doctor.
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If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and take the next dose at your regular time. Do not take 2 doses of OSENI at the same time.
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If you take too much OSENI, call your doctor or go to the nearest hospital emergency room right away.
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If your body is under stress, such as from fever, infection, accident or surgery, the dose of your diabetes medicines may need to be changed. Call your doctor right away.
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Stay on your diet and exercise programs and check your blood sugar as your doctor tells you to.
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Your doctor may do certain blood tests before you start OSENI and during treatment as needed. Your doctor may change your dose of OSENI based on the results of your blood tests due to how well your kidneys are working.
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Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your hemoglobin A1C.
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Your doctor should check your eyes regularly while you take OSENI.
What are the possible side effects of OSENI?

OSENI can cause serious side effects, including:

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See “What is the most important information I should know about OSENI? ”
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Allergic (hypersensitivity) reactions, such as:
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swelling of your face, lips, throat and other areas on your skin
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difficulty with swallowing or breathing
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raised, red areas on your skin (hives)
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skin rash, itching, flaking or peeling
If you have these symptoms, stop taking OSENI and contact your doctor right away.

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Liver problems. Call your doctor right away if you have unexplained symptoms such as:
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nausea or vomiting
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stomach pain
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unusual or unexplained tiredness
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loss of appetite
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dark urine
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yellowing of your skin or the whites of your eyes
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Broken bones (fractures). Usually in the hand, upper arm or foot in women. Talk to your doctor for advice on how to keep your bones healthy.
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Bladder cancer. There may be an increased chance of having bladder cancer when you take OSENI. You should not take OSENI if you are receiving treatment for bladder cancer. Tell your doctor right away if you have any of the following symptoms of bladder cancer:
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blood or a red color in your urine
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an increased need to urinate
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pain while you urinate
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Low blood sugar (hypoglycemia). If you take OSENI with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take OSENI. If you have symptoms of low blood sugar, you should check your blood sugar and treat if low, then c