Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

How should I use TOBI Podhaler?

See the step-by-step Instructions for Use at the end of this Patient Information leaflet about the right way to use TOBI Podhaler. Do not use TOBI Podhaler unless your healthcare provider has taught you how to use it the right way. Ask your healthcare provider or pharmacist if you are not sure.
Always use TOBI Podhaler exactly as your healthcare provider tells you to use it. Ask your healthcare provider or pharmacist if you are not sure.
The usual dose for adults and children over 6 years of age is:
The content of 4 TOBI Podhaler capsules inhaled by mouth in the morning using your Podhaler device and the content of 4 TOBI Podhaler capsules inhaled by mouth in the evening using your Podhaler device.
Check to see that each capsule is empty after inhaling. If powder remains in the capsule, repeat inhalation until the capsule is empty.
Each dose of 4 TOBI Podhaler capsules should be taken as close to 12 hours as possible.
You should not take your dose of 4 TOBI Podhaler capsules less than 6 hours apart.
If you forget to take TOBI Podhaler and there are at least 6 hours to your next dose, take your dose as soon as you can. Otherwise, wait for your next dose. Do not double the dose to make up for the missed dose.
After using TOBI Podhaler for 28 days, you should stop using it and wait 28 days. After you have stopped using TOBI Podhaler for 28 days, you should start using TOBI Podhaler again for 28 days. Complete the full 28 day course even if you are feeling better. It is important that you keep to the 28-day on, 28-day off cycle (See Figure A).

(Figure A)

If you are taking several different medicines inhaled through your mouth, your healthcare provider will tell you how to take your medicines the right way.
If you are doing therapies for cystic fibrosis (chest physiotherapy), you should take TOBI Podhaler after your therapies are done.
If you inhale too much TOBI Podhaler, tell your healthcare provider right away.
If you accidentally swallow TOBI Podhaler capsules, tell your healthcare provider right away.
Use a new Podhaler device every 7 days.
Caregivers should help children who are 10 years of age and younger use TOBI Podhaler, and should keep watching them use their TOBI Podhaler until they are able to use it the right way without help.
What are the possible side effects of TOBI Podhaler?

TOBI Podhaler can cause serious side effects, including:

hearing loss or ringing in the ears (ototoxicity). Tell your healthcare provider right away if you have hearing loss or you hear noises in your ears such as ringing or hissing. Tell your healthcare provider if you develop vertigo, difficulty with balance or dizziness.
worsening kidney problems (nephrotoxicity). TOBI Podhaler is in a class of drugs which may cause worsening kidney problems, especially in people with known or suspected kidney problems. Your healthcare provider may do a blood test to check how your kidneys are working while you are using TOBI Podhaler.
worsening muscle weakness. TOBI Podhaler is in a class of drugs which can cause muscle weakness to get worse in people who already have problems with muscle weakness (myasthenia gravis or Parkinson’s disease)