For babies who weigh 22 pounds or less, see the section below called “Instructions for giving Kuvan powder for oral solution (Kuvan 100 mg packets) to babies who weigh 22 pounds or less.”

Kuvan powder for oral solution should be dissolved in water or apple juice. The powder for oral solution may also be mixed in a small amount of soft foods, such as apple sauce or pudding. 

To dissolve Kuvan powder for oral solution:

Be sure that you know what dose of Kuvan your doctor has prescribed and whether you should use Kuvan 100 mg packets, Kuvan 500 mg packets, or both types of packets to prepare your dose.

Open the packet(s) of Kuvan powder for oral solution by folding and tearing, or cutting at the dotted line in the upper right corner of the packet. Open the packet(s) only when you are ready to use them.

Empty the contents of the packet(s) into 4 ounces to 8 ounces (1/2 cup to 1 cup) of water or apple juice.

Drink within 30 minutes. 
Instructions for giving Kuvan powder for oral solution (Kuvan 100 mg packets) to babies who weigh 22 pounds or less:

The dose of Kuvan is based on body weight. This will change as your baby grows. Your doctor will tell you:
the number of Kuvan 100 mg packets needed for one dose
the amount of water or apple juice needed to mix one dose of Kuvan
the amount of the mixture (powder and water or apple juice) you will need to give your baby his or her prescribed dose of medicine.
Give your baby the prescribed amount of mixture (powder and water or apple juice) within 30 minutes after mixing. If you are not able to give your baby’s dose within 30 minutes after mixing, pour the unused medicine into the trash. You will need to mix a new dose.
Supplies needed to mix and give your baby’s dose of Kuvan powder for oral solution:

the number of Kuvan 100 mg packets needed for one dose
a small cup of water or apple juice
one 30 mL medicine cup for mixing
small spoon or clean utensil for mixing
10 mL oral dosing syringe
scissors (optional)
Ask your pharmacist for a 30 mL medicine cup for mixing and an oral dosing syringe if you do not have these supplies.

Step 1: Find a clean, flat work surface.  
Step 2:   Place a small cup of water or apple juice, the oral dosing syringe, and an empty medicine cup on your clean, flat work surface (see Figure A). 
Figure A
 
Step 3: Pour 5 mL or 10 mL of water or apple juice from the small cup into the medicine cup, as instructed by your doctor. Check to make sure that the amount of liquid lines up with the amount that your doctor tells you (see Figure B). 
Figure B
 
Step 4: Check the label on the Kuvan packet(s). If the packet is marked Kuvan 100 mg, empty the entire contents of the Kuvan packet into the medicine cup (see Figure C). 
Figure C
 
Step 5:  Stir the mixture with the small spoon or other clean utensil until all of the powder completely dissolves (see Figure D). 
Figure D
 
Step 6: To give a dose of Kuvan to your baby:  Place the tip of the oral dosing syringe into the liquid inside the medicine cup. Pull back on the plunger and draw up the amount of the mixture prescribed by your doctor (see Figure E). 
Figure E
 
Step 7: Take the oral dosing syringe out of the medicine cup. Carefully turn the oral dosing syringe so that the tip is pointing up. Check to m