g to become pregnant. See “What is the most important information I should know about JUXTAPID?”
take medicines that affect how the body breaks down JUXTAPID (that is, strong or moderate CYP3A4 inhibitors). Check with your doctor and/or pharmacist to see if you are taking any of these medications. These may include certain medications intended to treat bacterial, fungal or viral infections, and medications to treat depression, high blood pressure, or angina.
drink grapefruit juice
have moderate or severe liver problems or active liver disease, including people who have unexplained abnormal liver tests.
What should I tell my doctor before taking JUXTAPID?
Before you take JUXTAPID, tell your doctor if you:
have liver problems
have kidney problems
have intestine or bowel problems
drink alcohol
are breastfeeding or plan to breastfeed. It is not known if JUXTAPID passes into your breast milk. You and your doctor should decide if you will take JUXTAPID or breastfeed. You should not do both.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Before starting a new medicine while taking JUXTAPID, even if you will only be taking it for a short time, ask your doctor or pharmacist if it is safe to take with JUXTAPID.
JUXTAPID may affect the way other medicines work, and other medicines may affect how JUXTAPID works.
Certain medicines can affect how your liver breaks down other medicines.
Especially tell your doctor if you take:
a blood thinner called warfarin
medicines for high cholesterol, including statins such as atorvastatin or simvastatin, and resins such as colesevelam or cholestyramine
medicines for bacteria, fungus, or viral infection (including HIV and hepatitis C)
medicines for depression, high blood pressure, or angina
birth control pills
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
How should I take JUXTAPID?
Take JUXTAPID exactly as your doctor tells you to take it.
Your doctor will tell you how much JUXTAPID to take and when to take it.
Your doctor may change your dose of JUXTAPID if needed.
Do not change your JUXTAPID dose yourself.
Take JUXTAPID 1 time each day at least 2 hours after your evening meal.
Take JUXTAPID with water.
You should not take JUXTAPID with food. Taking JUXTAPID with food may cause stomach problems.
Take JUXTAPID capsules whole. Do not open, crush, dissolve, or chew capsules before swallowing. If you cannot swallow JUXTAPID capsules whole, tell your doctor. You may need a different medicine.
If you take a medicine that lowers cholesterol by binding bile acids, such as colesevelam or cholestyramine, take it at least 4 hours before or 4 hours after you take JUXTAPID. Ask your doctor if you are not sure if you take these medicines.
To help lower the chance of stomach problems, stay on a low-fat diet. Ask your doctor about talking to a dietician to learn what you should eat while taking JUXTAPID. JUXTAPID makes it harder for some nutrients to get into your body. Take Vitamin E and fatty acids each day while you take JUXTAPID. Ask your doctor, nurse, or dietician how to add them to your diet.
If you take too much JUXTAPID, call your doctor right away.
Do not stop JUXTAPID unless your doctor tells you to stop it.
If you miss a dose of JUXTAPID, take your usual dose the next day at the usual time. If you stop taki
