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Avelox 400 mg/250 ml solution for infusion(七)
2015-05-10 20:44:46 来源: 作者: 【 】 浏览:5941次 评论:0
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Palpitations

Tachycardia

Atrial fibrillation

Angina pectoris
 Ventricular tachyarrhythmias

Syncope (i.e., acute and short lasting loss of consciousness)
 Unspecified arrhythmias

Torsade de Pointes (see section 4.4)

Cardiac arrest (see section 4.4)
 
Vascular disorders
   Vasodilatation
 Hypertension

Hypotension
  
Respiratory, thoracic and mediastinal disorders
   Dyspnea (including asthmatic conditions)
    
Gastrointestinal disorders
 Nausea

Vomiting

Gastrointestinal and abdominal pains

Diarrhoea
 Decreased appetite and food intake

Constipation

Dyspepsia

Flatulence

Gastritis

Increased amylase
 Dysphagia

Stomatitis

Antibiotic-associated colitis (incl. pseudo-membranous colitis, in very rare cases associated with life-threatening complications, see section 4.4)
  
Hepatobiliary disorders
 Increase in transaminases
 Hepatic impairment (incl. LDH increase)

Increased bilirubin

Increased gamma-glutamyl-transferase

Increase in blood alkaline phosphatase
 Jaundice

Hepatitis (predominantly cholestatic)
 Fulminant hepatitis potentially leading to life-threatening liver failure (incl. fatal cases, see section 4.4)
 
Skin and subcutaneous tissue disorders
   Pruritus

Rash

Urticaria

Dry skin
   Bullous skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis (potentially life-threatening, see section 4.4)
 
Musculoskeletal andconnective tissue disorders
   Arthralgia

Myalgia
 Tendonitis (see section 4.4)

Muscle cramp

Muscle twitching

Muscle weakness
 Tendon rupture (see section 4.4)

Arthritis

Muscle rigidity

Exacerbation of symptoms of myasthenia gravis (see section 4.4)
 
Renal and urinary disorders
   Dehydration
 Renal impairment (incl. increase in BUN and creatinine)

Renal failure (see section 4.4)
  
General disorders and administration site conditions
 Injection and infusion site reactions
 Feeling unwell (predominantly asthenia or fatigue)

Painful conditions (incl. pain in back, chest, pelvic and extremities)

Sweating

Infusion site (thrombo-) phlebitis
 Oedema
  

The following undesirable effects have a higher frequency category in the subgroup of IV treated patients with or without subsequent oral therapy:


Common:  Increased gamma-glutamyl-transferase 
Uncommon:  Ventricular tachyarrhythmias, hypotension, oedema, antibiotic-associated colitis (incl. pseudomembranous colitis, in very rare cases associated with life-threatening complications, see section 4.4), seizures incl. grand mal convulsions (see section 4.4), hallucination, renal impairment (incl. increase in BUN and creatinine), renal failure (see section 4.4) 

There have been very rare cases of the following side effects reported following treatment with other fluoroquinolones, which might possibly also occur during treatment with moxifloxacin: hypernatrae

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