7. Gastrointestinal Diseases
To tide the patient over a critical period of the disease in:
Ulcerative colitis (systemic therapy) Regional enteritis (systemic therapy)

8. Respiratory Diseases
Symptomatic sarcoidosis Loeffler’s syndrome not manage-
Berylliosis able by other means
Fulminating or disseminated pulmonary Aspiration pneumonitis tuberculosis when used concurrently with appropriate antituberculous chemotherapy

9. Hematologic Disorders
Acquired (autoimmune) hemolytic anemia Erythroblastopenia (RBC anemia)
Idiopathic thrombocytopenic purpura Congenital (erythroid) hypoplastic in adults (IV only; IM administration anemia is contraindicated)
Secondary thrombocytopenia in adults

10. Neoplastic Diseases
For palliative management of:
Leukemias and lymphomas in adults Acute leukemia of childhood

11. Edematous States
To induce diuresis or remission of proteinuria in the nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus

12. Nervous System
Acute exacerbations of multiple sclerosis

13. Miscellaneous
Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy
Trichinosis with neurologic or myocardial involvement

Contraindications
The use of SOLU-MEDROL Sterile Powder is contraindicated in premature infants because the 40 mg Act-O-Vial, the 125 mg Act-O-Vial, the 500 mg Act-O-Vial, the 1 gram Act-O-Vial system, and the accompanying diluent for the 500 mg and 2 gram vials contain benzyl alcohol. Benzyl alcohol has been reported to be associated with a fatal "Gasping syndrome" in premature infants.
SOLU-MEDROL Sterile Powder is also contraindicated in systemic fungal infections and patients with known hypersensitivity to the product and its constituents.

Warnings
In patients on corticosteroid therapy subjected to any unusual stress, increased dosage of rapidly acting corticosteroids before, during, and after the stressful situation is indicated.

Corticosteroids may mask some signs of infection, and new infections may appear during their use. There may be decreased resistance and inability to localize infection when corticosteroids are used. Infections with any pathogen including viral, bacterial, fungal, protozoan or helminthic infections, in any location of the body, may be associated with the use of corticosteroids alone or in combination with other immunosuppressive agents that affect cellular immunity, humoral immunity, or neutrophil function.1

These infections may be mild, but can be severe and at times fatal. With increasing doses of corticosteroids, the rate of occurrence of infectious complications increases.2

A study has failed to establish the efficacy of SOLU-MEDROL in the treatment of sepsis syndrome and septic shock. The study also suggests that treatment of these conditions with SOLU-MEDROL may increase the risk of mortality in certain patients (i.e., patients with elevated serum creatinine levels or patients who develop secondary