g prescription medicines and non-prescription medicines, vitamins, and herbal supplements. Using SUTENT with certain other medicines can cause serious side effects.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Talk with your healthcare provider before starting any new medicines.
How should I take SUTENT?
Take SUTENT exactly the way your healthcare provider tells you.
Take SUTENT 1 time each day with or without food.
If you take SUTENT for GIST or RCC, you will usually take your medicine for 4 weeks (28 days) and then stop for 2 weeks (14 days). This is 1 cycle of treatment. You will repeat this cycle for as long as your healthcare provider tells you to.
If you take SUTENT for pNET, take it one time each day until your healthcare provider tells you to stop.
Do not open the SUTENT capsules.
Do not drink grapefruit juice or eat grapefruit during your treatment with SUTENT. They may cause you to have too much SUTENT in your body.
Your healthcare provider may do blood tests before each cycle of treatment.
If you miss a dose, take it as soon as you remember. Do not take it if it is close to your next dose. Just take the next dose at your regular time. Do not take more than 1 dose of SUTENT at a time. Tell your healthcare provider about any missed dose.
Call your healthcare provider right away, if you take too much SUTENT.
What are possible side effects of SUTENT?
SUTENT may cause serious side effects including:
See "What is the most important information I should know about SUTENT?"
Heart problems. Heart problems may include heart failure and heart muscle problems (cardiomyopathy) that can lead to death. Tell your healthcare provider if you feel very tired, are short of breath, or have swollen feet and ankles.
Abnormal heart rhythm changes. Your healthcare provider may do electrocardiograms and blood tests to watch for these problems during your treatment with SUTENT. Tell your healthcare provider if you feel dizzy, faint, or have abnormal heartbeats while taking SUTENT.
High blood pressure. Your healthcare provider may check your blood pressure during treatment with SUTENT. Your healthcare provider may prescribe medicine for you to treat high blood pressure, if needed.
Bleeding sometimes leading to death. Tell your healthcare provider right away if you have any of these symptoms or a serious bleeding problem during treatment with SUTENT.
painful, swollen stomach (abdomen)
vomiting blood
black, sticky stools
bloody urine
headache or change in your mental status
Your healthcare provider can tell you other symptoms to watch for.
Hormone problems, including thyroid and adrenal gland problems. Your healthcare provider may do tests to check your thyroid and adrenal gland function during SUTENT treatment. Tell your doctor if you have any of the following signs and symptoms during treatment with SUTENT:
tiredness that worsens and does not go away
loss of appetite
heat intolerance
feeling nervous or agitated, tremors
sweating
nausea or vomiting
diarrhea
fast heart rate
weight gain or weight loss
feeling depressed
irregular menstrual periods or no menstrual periods
headache
hair loss
Common side effects of SUTENT include:
The medicine in SUTENT is yellow, and it may make your skin look yellow. Your skin and hair may get lighter in color.
tiredness
weakness
fever
gastrointestinal symptoms, in |
