y common
Thrombocytopoenia
14 (16.9%)
2 (2.4%)
1 (1.2%)
Common
Leukopoenia
8 (9.6%)
4 (4.8%)
1 (1.2%)
Endocrine disorders
Common
Hypothyroidism
5 (6.0%)
0 (0.0%)
0 (0.0%)
Metabolism and nutrition disorders
Very common
Anorexia
17 (20.5%)
2 (2.4%)
0 (0.0%)
Common
Decrease appetite
5 (6.0%)
0 (0.0%)
0 (0.0%)
Psychiatric disorders
Common
Insomnia
7 (8.4%)
0 (0.0%)
0 (0.0%)
Nervous system disorders
Very common
Dysgeusia
16 (19.3%)
0 (0.0%)
0 (0.0%)
Very common
Headache
10 (12.0%)
0 (0.0%)
0 (0.0%)
Common
Dizziness
5 (6.0%)
1 (1.2%)
0 (0.0%)
Eye disorders
Common
Eyelid oedema
5 (6.0%)
1 (1.2%)
0 (0.0%)
Vascular disorders
Very common
Hypertension
19 (22.9%)
8 (9.6%)
0 (0.0%)
Respiratory, thoracic and mediastinal disorders
Very common
Epistaxis
16 (19.3%)
1 (1.2%)
0 (0.0%)
Common
Dyspnoea
6 (7.2%)
1 (1.2%)
0 (0.0%)
Gastrointestinal disorders
Very common
Diarrhoea
44 (53.0%)
4 (4.8%)
0 (0.0%)
Very common
Nausea
32 (38.6%)
1 (1.2%)
0 (0.0%)
Very common
Vomiting
21 (25.3%)
0 (0.0%)
0 (0.0%)
Very common
Stomatitis
18 (21.7%)
3 (3.6%)
0 (0.0%)
Very common
Abdominal pain
12 (14.5%)
1 (1.2%)
0 (0.0%)
Very common
Dyspepsia
12 (14.5%)
0 (0.0%)
0 (0.0%)
Common
Constipation
8 (9.6%)
0 (0.0%)
0 (0.0%)
Common
Dry mouth
7 (8.4%)
0 (0.0%)
0 (0.0%)
Common
Abdominal pain upper
6 (7.2%)
1 (1.2%)
0 (0.0%)
Common
Aphtous stomatitis
5 (6.0%)
0 (0.0%)
0 (0.0%)
Common
Flatulence
5 (6.0%)
0 (0.0%)
0 (0.0%)
Common
Gingival bleeding
5 (6.0%)
0 (0.0%)
0 (0.0%)
Skin and subcutaneous tissue disorders
Very common
Hair colour changes
24 (28.9%)
1 (1.2%)
0 (0.0%)
Very common
Palmar-plantar erythrodysaesthesia syndrome
19 (22.9%)
5 (6.0%)
0 (0.0%)
Very common
Rash
13 (15.7%)
0 (0.0%)
0 (0.0%)
Very common
Dry skin
11 (13.3%)
0 (0.0%)
0 (0.0%)
Common
Nail disorder
8 (9.6%)
0 (0.0%)
0 (0.0%)
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