ABRAXANE® is a registered trademark of Abraxis BioScience, LLC.
©2005-2014 Abraxis BioScience, LLC.
All Rights Reserved.
Abraxis BioScience, LLC is a wholly owned subsidiary of Celgene Corporation.
U.S. Patent Numbers: See www.celgene.com.
ABRPI.008/PPI.008 12/14
PATIENT PACKAGE INSERT
Patient Information
ABRAXANE® (ah-BRAKS-ane)
(paclitaxel protein-bound particles for injectable suspension)
(albumin-bound)
Read this Patient Information before you start receiving ABRAXANE and before each infusion. This information does not take the place of talking with your doctor about your medical condition or your treatment.
What is ABRAXANE?
ABRAXANE is a prescription medicine used to treat:
advanced breast cancer in people who have already received certain other medicines for their cancer.
advanced non-small cell lung cancer, in combination with carboplatin in people who cannot be treated with surgery or radiation.
and advanced pancreatic cancer, when used in combination with gemcitabine as the first medicine for advanced pancreatic cancer.
It is not known if ABRAXANE is safe or effective in children.
Who should not receive ABRAXANE?
Do not receive ABRAXANE if:
your white blood cell count is below 1,500 cells/ mm3.
you have had a severe allergic reaction to ABRAXANE.
What should I tell my doctor before receiving ABRAXANE?
Before you receive ABRAXANE, tell your doctor if you:

have liver or kidney problems.
have any other medical conditions.
are a man planning to father a child. You should not father a child during your treatment with ABRAXANE. ABRAXANE can harm the unborn baby of your partner. Talk to your doctor if this is a concern to you.
are pregnant or plan to become pregnant. ABRAXANE can harm your unborn baby. You should not become pregnant while receiving ABRAXANE. Women who may become pregnant should use effective birth control (contraception). Talk to your doctor about the best way to prevent pregnancy while receiving ABRAXANE.
are breastfeeding or plan to breastfeed. It is not known if ABRAXANE passes into your breast milk. You and your doctor should decide if you will receive ABRAXANE or breastfeed.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Know the medicines you take. Keep a list to show your doctor and pharmacist when you get a new medicine.
How will I receive ABRAXANE?
Your doctor will prescribe ABRAXANE in an amount that is right for you.
Premedication to prevent allergic reactions is generally not needed to receive ABRAXANE. Premedication may be needed if you have had an allergic reaction to ABRAXANE. In case of severe allergic reaction, ABRAXANE should not be used again.
ABRAXANE will be given to you by intravenous infusion into your vein.
Your doctor should do regular blood tests while you receive ABRAXANE.
What are the possible side effects of ABRAXANE?

ABRAXANE may cause serious side effects, including:

decreased blood cell counts. ABRAXANE can cause a severe decrease in neutrophils (a type of white blood cells important in fighting against bacterial infections) and platelets (important for clotting and to control bleeding). Your doctor will check your blood cell count during your treatment with ABRAXANE and after you have stopped your treatment.