Before you take VIMOVO, tell your healthcare provider about all your medical conditions, including if you:

have been told that you have low magnesium levels in your blood

have liver or kidney problems

have ulcerative colitis or Crohn’s disease (inflammatory bowel disease or IBD)

have any other medical conditions

are pregnant or plan to become pregnant. See “What is the most important information I should know about VIMOVO?”

are breast-feeding or plan to breast-feed. VIMOVO can pass into your milk and may harm your baby. You should not breast-feed while taking VIMOVO. Talk to your healthcare provider about the best way to feed your baby if you take VIMOVO.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Since VIMOVO contains naproxen, talk to your healthcare provider before taking any other NSAID-containing products.

Especially tell your healthcare provider if you take:

steroid hormones (corticosteroids)
St. John's Wort

rifampin (Rifater, Rifamate, Rimactane, Rifadin)

a medicine for high blood pressure or heart problems

aspirin

cholestyramine (Questran, Questran Light, Locholest, Locholest Light, Preva lite)

cyclosporine (Gengraf, Neoral, Sandimmune) or tacrolimus (Prograf)

a water pill (diuretic)

lithium carbonate

methotrexate sodium (Trexall)

blood thinner medicines, including warfarin sodium (Coumadin, Jantoven), dicumarol, or a blood thinner that contains heparin

an antidepressant medicine

Ask your healthcare provider if you are not sure if your medicine is one that is listed above.

Using VIMOVO with other medicines can cause serious side effects. VIMOVO may affect the way other medicines work, and other medicines may affect how VIMOVO works.

Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.

How should I take VIMOVO?

Take VIMOVO exactly as your healthcare provider tells you to take it.

Your healthcare provider may tell you to take Vitamin D and Calcium supplements during treatment with VIMOVO.

Your healthcare provider will tell you how many VIMOVO to take and when to take them.

Do not change your dose or stop VIMOVO without first talking to your healthcare provider.

Take VIMOVO at least 30 minutes before a meal.

Swallow VIMOVO tablets whole with liquid. Do not split, chew, crush or dissolve the VIMOVO tablet. Tell your healthcare provider if you cannot swallow the tablet whole. You may need a different medicine.

You may use antacids while taking VIMOVO.

If you forget to take a dose of VIMOVO, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose. Take the next dose on time. Do not take 2 doses at one time to make up for a missed dose.

If you take too much VIMOVO, tell your healthcare provider or go to the closest hospital emergency room right away. Symptoms that you have taken too much VIMOVO may include:

feeling weak and tired

dizziness

feeling sleepy

upper stomach-area pain or discomfort

heartburn, indigestion, or nausea

a change in breathing or you stop breathing

vomiting

bleeding

movements of a body part that you cannot control

coordination p