y salts (electrolytes). Death has happened from having severe diarrhea and losing too much body fluid or body salts with JEVTANA. Tell your doctor if you have vomiting or diarrhea. Your doctor will prescribe medicines to prevent or treat vomiting and diarrhea, as needed with JEVTANA. Tell your doctor if your symptoms get worse or do not get better. You may need to go to the hospital for treatment.
Kidney failure. Kidney failure may happen with JEVTANA, because of severe infection, loss of too much body fluid (dehydration), and other reasons, which may lead to death. Your doctor will check you for this problem and treat you if needed. Tell your doctor if you develop:
swelling of your face or body
decrease in the amount of urine that your body makes each day.
What is JEVTANA?
JEVTANA is a prescription anti-cancer medicine used with the steroid medicine prednisone. JEVTANA is used to treat people with prostate cancer that has worsened (progressed) after treatment with other anti-cancer medicines, including docetaxel.
It is not known if JEVTANA is safe and works in children.
Who should not receive JEVTANA?
Do not receive JEVTANA if:
your white blood cell (neutrophil count) is too low
you have had a severe allergic reaction to cabazitaxel or other medicines that contain polysorbate 80. Ask your doctor if you are not sure.
What should I tell my doctor before receiving JEVTANA?
Before receiving JEVTANA, tell your doctor if you:
had allergic reactions in the past
have kidney or liver problems
are over the age of 65
have any other medical conditions
if you are a female and:
are pregnant or plan to become pregnant. JEVTANA can harm your unborn baby. Talk to your doctor about the best way for you to prevent pregnancy while you are receiving JEVTANA.
are breastfeeding or plan to breastfeed. It is not known if JEVTANA passes into your breast milk. You and your doctor should decide if you will take JEVTANA or breastfeed. You should not do both.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. JEVTANA can interact with many other medicines. Do not take any new medicines without asking your doctor first. Your doctor will tell you if it is safe to take the new medicine with JEVTANA.
How will I receive JEVTANA?
JEVTANA will be given to you by an intravenous (IV) infusion into your vein.
Your treatment will take about 1 hour.
JEVTANA is usually given every 3 weeks. Your doctor will decide how often you will receive JEVTANA .
Your doctor will also prescribe another medicine called prednisone, for you to take by mouth every day during treatment with JEVTANA. Your doctor will tell you how and when to take your prednisone.
It is important that you take prednisone exactly as prescribed by your doctor. If you forget to take your prednisone, or do not take it on schedule, make sure to tell your doctor or nurse. Before each infusion of JEVTANA, you may receive other medicines to prevent or treat side effects.
What are the possible side effects of JEVTANA?
JEVTANA may cause serious side effects including:
See "What is the most important information I should know about JEVTANA?"
Common side effects of JEVTANA include:
Low red blood cell count (anemia). Your doctor will regularly check your red blood cell count. Symptoms of anemia include shortness of breath and tiredness.
Low blood platelet count. Tell your doctor if you have any unus
