Keep JANUMET and all medicines out of the reach of children.

General information about the use of JANUMET

Medicines are sometimes prescribed for purposes other than those listed in Medication Guides. Do not use JANUMET for a condition for which it was not prescribed. Do not give JANUMET to other people, even if they have the same symptoms you have. It may harm them.

This Medication Guide summarizes the most important information about JANUMET. If you would like to know more information, talk with your doctor. You can ask your doctor or pharmacist for additional information about JANUMET that is written for health care professionals. For more information go to www.JANUMET.com or call 1-800-622-4477.

What are the ingredients in JANUMET?

Active ingredients: sitagliptin and metformin hydrochloride

Inactive ingredients: microcrystalline cellulose, polyvinylpyrrolidone, sodium lauryl sulfate, and sodium stearyl fumarate. The tablet film coating contains the following inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, red iron oxide, and black iron oxide.

What is type 2 diabetes?

Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems.

High blood sugar can be lowered by diet and exercise, and by certain medicines when necessary.

JANUMET® and JANUVIA® are registered trademarks of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.

Avandia® is a registered trademark of GlaxoSmithKline.

Copyright © 2010 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
All rights reserved

Revised April 2011

Dist. by: Merck Sharp & Dohme Corp., a subsidiary of
MERCK & CO., INC., Whitehouse Station, NJ 08889, USA

9984503

US Patent No.: 6,699,871

This Medication Guide has been approved by the U.S. Food and Drug Administration.

This is a representative sample of the packaging. Please see How Supplied section for a complete list of available packaging.

PRINCIPAL DISPLAY PANEL - Bottle Label 50 mg/500 mg

Janumet®
(sitagliptin/metformin HCl) tablets

50 mg/500 mg

Rx only

60 Tablets

NDC 0006-0575-61

Each tablet contains 64.25 mg sitagliptin phosphate (equivalent to 50 mg sitagliptin) and 500 mg metformin hydrochloride.

Dispense the accompanying Medication Guide to each patient.

Store at 20-25°C (68-77°F), excursions permitted to 15-30°C (59-86°F). [See USP Controlled Room Temperature.]

See accompanying circular for dosage information.

Merck Sharp & Dohme Corp., a subsidiary of
MERCK & CO., INC.
Whitehouse Station, NJ 08889, USA

7001164700
60 | No. 6747

PRINCIPAL DISPLAY PANEL - Bottle Label 50 mg/1000 mg

Janumet®
(sitagliptin/metformin HCl) tablets

50 mg/1000 mg

Rx only

60 Tablets

NDC 0006-0577-61

Each tablet contains 64.25 mg sitagliptin phosphate (equivalent to 50 mg sitagliptin) and 1000 mg metformin hydrochloride.

Dispense the accompanying Medication Guide to each patient.

Store at 20-25°C (68-77°F), excursions permitted to 15