a short time. Call your doctor for instructions if you:
are dehydrated (have lost too much body fluid). Dehydration can occur if you are sick with severe vomiting, diarrhea or fever, or if you drink a lot less fluid than normal.
plan to have surgery.
are going to get an injection of dye or contrast agent for an x-ray procedure. See "What is the most important information I should know about JANUMET?" and "Who should not take JANUMET?".
When your body is under some types of stress, such as fever, trauma (such as a car accident), infection or surgery, the amount of diabetes medicine that you need may change. Tell your doctor right away if you have any of these problems and follow your doctor’s instructions.
Check your blood sugar as your doctor tells you to.
Stay on your prescribed diet and exercise program while taking JANUMET.
Talk to your doctor about how to prevent, recognize and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and problems you have because of your diabetes.
Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your hemoglobin A1C.
Your doctor will do blood tests to check how well your kidneys are working before and during your treatment with JANUMET.
What are the possible side effects of JANUMET?
Serious side effects have happened in people taking JANUMET.
See "What is the most important information I should know about JANUMET?".
Low blood sugar (hypoglycemia). If you take JANUMET with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUMET. Signs and symptoms of low blood sugar may include:
headache
drowsiness
weakness
dizziness
confusion
irritability
hunger
fast heart beat
sweating
feeling jittery
Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking JANUMET and call your doctor right away. See "Who should not take JANUMET?". Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes.
Kidney problems, sometimes requiring dialysis.
The most common side effects of JANUMET include:
stuffy or runny nose and sore throat
upper respiratory infection
diarrhea
nausea and vomiting
gas, upset stomach, indigestion
weakness
headache
Taking JANUMET with meals can help lessen the common stomach side effects of metformin that usually happen at the beginning of treatment. If you have unusual or sudden stomach problems, talk with your doctor. Stomach problems that start later during treatment may be a sign of something more serious.
JANUMET may have other side effects, including:
swelling of the hands or legs. Swelling of the hands and legs can happen if you take JANUMET in combination with rosiglitazone (Avandia®). Rosiglitazone is another type of diabetes medicine.
These are not all the possible side effects of JANUMET. For more information, ask your doctor or pharmacist.
Tell your doctor if you have any side effect that bothers you, is unusual, or does not go away.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How should I store JANUMET?
Store JANUMET at 68&de
