For doctors
What is it and how is it used?
BYDUREON is an injectable medicine used to improve blood sugar control in adults with type 2 diabetes mellitus.

BYDUREON is used in combination with the following diabetes medicines: metformin, sulphonylureas and thiazolidinediones. Your doctor is now prescribing BYDUREON as an additional medicine to help control your blood sugar. Continue to follow your food and exercise plan.

You have diabetes because your body does not make enough insulin to control the level of sugar in your blood or your body is not able to use the insulin properly. BYDUREON helps your body to increase the production of insulin when your blood sugar is high.

What do you have to consider before using it?
Do not use BYDUREON

Take special care with BYDUREON

Using other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including warfarin and including medicines obtained without a prescription.

The use of BYDUREON with insulins, and other medicines that are used to treat type 2 diabetes that work like BYDUREON (for example:liraglutide and Byetta [exenatide twice daily]), is not recommended.

Using BYDUREON with food and drink

Use BYDUREON at any time of day, with or without meals.

Pregnancy and breast-feeding

Women of childbearing potential should use contraception during treatment with BYDUREON. It is not known if BYDUREON may harm your unborn child. Tell your doctor if you are, you think you might be, or are planning to become pregnant as BYDUREON should not be used during pregnancy and for at least three months before a pregnancy.

It is not known if BYDUREON passes into your milk. BYDUREON should not be used if breast-feeding.

Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

If you use BYDUREON in combination with a sulphonylurea, low blood sugar (hypoglycaemia) can occur. Hypoglycaemia may reduce your ability to concentrate. Please keep this possible problem in mind in all situations where you might put yourself and others at risk (e.g. driving a car or operating machines).

Important information about some of the ingredients of BYDUREON

This medicine contains less than 1 mmol sodium (23 mg) per dose, i.e. essentially “sodium-free”.

How is it used?
Always use BYDUREON exactly as your doctor or diabetes nurse has told you. You should check with your doctor, diabetes nurse or pharmacist if you are unsure.

BYDUREON 2 mg should be injected once a week, at any time of day, with or without meals.

BYDUREON is injected into the skin (subcutaneous injection) of your stomach area (abdomen), upper leg (thigh), or the back of your upper arm.
Each week you can use the same area of your body. But be sure to choose a different injection site in that area.

Test your blood glucose levels regularly, it is particularly important to do this if you are also using a sulphonylurea.

Follow the Instructions for the User provided in the carton to inject BYDUREON

Your health care professional should teach you how to inject BYDUREON before you use it for the first time.

Check that the liquid in the syringe is clear and free of particles before you begin. After mixing use the suspension only if the mixture is white to off white and cloudy. If you see clumps of dry powder on the sides or bottom of the vial, the medicine is NOT mixed well. Shake vigorously again until well mi