Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever
the solution and container permit. The Injection is not to be used if its color is pinkish or darker than slightly yellow or if it contains a
precipitate.
Table 1: Recommended Dosages
Procedure
Xylocaine (lidocaine hydrochloride) Injection (without epinephrine)
Conc (%)
Vol (mL)
Total Dose (mg)
Infiltration
Percutaneous
0.5 or 1
1 to 60
5 to 300
Intravenous regional
0.5
10 to 60
50 to 300
Peripheral Nerve Blocks, eg,
Brachial
1.5
15 to 20
225 to 300
Dental
2
1 to 5
20 to 100
Intercostal
1
3
30
Paravertebral
1
3 to 5
30 to 50
Prudendal (each side)
1
10
100
Paracervical
Obstetrical analgesia
(each side)
1
10
100
Sympathetic Nerve Blocks, eg,
Cervical (stellate ganglion)
1
5
50
Lumbar
1
5 to 10
50 to 100
Central Neural Blocks
Epidural*
Thoracic
1
20 to 30
200 to 300
Lumbar
Analgesia
1
25 to 30
250 to 300
Anesthesia
1.5
15 to 20
225 to 300
2
10 to 15
200 to 300
Caudal
Obstetrical analgesia
1
20 to 30
200 to 300
Surgical anesthesia
1.5
15 to 20
225 to 300
*Dose determined by number of dermatomes to be anesthetized (2 to 3 mL/dermatome).
THE ABOVE SUGGESTED CONCENTRATIONS AND VOLUMES SERVE ONLY AS A GUIDE. OTHER VOLUMES AND
CONCENTRATIONS MAY BE USED PROVIDED THE TOTAL MAXIMUM RECOMMENDED DOSE IS NOT EXCEEDED.
STERILIZATION, STORAGE AND TECHNICAL PROCEDURES
Disinfecting agents containing heavy metals, which cause release of respective ions (mercury, zinc, copper, etc) should not be used
for skin or mucous membrane disinfection as they have been related to incidents of swelling and edema. When chemical disinfection
of multi-dose vials is desired, either isopropyl alcohol (91%) or ethyl alcohol (70%) is recommended. Many commercially available
brands of rubbing alcohol, as well as solutions of ethyl alcohol not of USP grade, contain denaturants which are injurious to rubber
and therefore are not to be used.
Dosage forms listed as Xylocaine-MPF indicate single dose solutions that are Methyl Paraben Free (MPF).
HOW SUPPLIED
Xylocaine-MPF
Xylocaine
&n