Tell your doctor about all of your medical conditions including if you:

have kidney problems.
have liver problems.
have heart problems.
drink a lot of alcohol.
are pregnant or planning to become pregnant. It is not known if GLUMETZA can harm your unborn baby. Talk to your doctor about the best way to control your blood sugar levels while pregnant.
are breastfeeding. It is not known if GLUMETZA passes into your milk and if it can harm your baby. Talk to your doctor about the best way to feed your baby while taking GLUMETZA.
Tell your doctor about all the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements. GLUMETZA and some of your other medicines can interact. You may need to have the dose of GLUMETZA or certain other medicines adjusted. Certain other medicines can affect your blood sugar control.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist. Talk to your doctor before you start any new medicine.

How should I take GLUMETZA?

Take GLUMETZA exactly as prescribed. Your doctor will usually start you on a low dose and increase your dose slowly to control your blood sugar levels. Do not change your dose unless told to do so by your doctor.
Take GLUMETZA once a day in the evening with food.
Swallow GLUMETZA tablets whole. Never crush, split or chew GLUMETZA tablets. Tell your doctor if you cannot swallow tablets whole. Your doctor will prescribe a different medicine for you.
You may see the GLUMETZA tablet shell in your stool. You may also see a soft mass of the GLUMETZA inactive ingredients in your stool. Both of these are normal to see in your stool.
Stay on your exercise and diet program and test your blood sugar regularly while taking GLUMETZA.
Your doctor should monitor your diabetes and do blood tests on you from time to time to check your kidneys and your liver.
If you miss a dose of GLUMETZA resume dosing according to schedule.
If you take too much GLUMETZA or overdose, call your doctor or poison control center right away.
You may need to stop GLUMETZA for a short period of time if you:
are sick with severe vomiting, diarrhea or fever, or if you drink a much lower amount of liquid than normal.
plan to have surgery.
are having an x-ray procedure with an injection of dye.
Call your doctor right away for instructions.

What should I avoid while taking GLUMETZA?

Do not drink a lot of alcoholic drinks while taking GLUMETZA. This means you should not binge drink for short periods, and you should not drink a lot of alcohol on a regular basis. Alcohol can increase the chance of getting lactic acidosis.

What are the side effects of GLUMETZA?

GLUMETZA can cause a rare, but serious side effect called lactic acidosis (a buildup of an acid in your blood) that can cause death. See"What is the most important information I should know about GLUMETZA?"

The most common side effects of GLUMETZA include diarrhea, nausea, and upset stomach. These side effects usually go away after you take the medicine for a while. Taking your medicine with the evening meal can help reduce these side effects.

GLUMETZA rarely causes low blood sugar (hypoglycemia) by itself. However, low blood sugar can happen if you do not eat enough, if you drink alcohol, or if you take other medicines to lower blood sugar.

Tell your doctor if you have side effects that bother you, last for more than a few weeks, come back after they have gone aw