ull;
swelling of the face, arms, or legs
MEKINIST can cause new or worsening high blood pressure (hypertension). Your healthcare provider should check your blood pressure during treatment with MEKINIST. Tell your healthcare provider if you develop high blood pressure, your blood pressure worsens, or you have severe headache, lightheadedness, or dizziness.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of MEKINIST. For more information, ask your healthcare provider or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How should I store MEKINIST?
•
Store MEKINIST in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze.
•
Keep MEKINIST dry and away from moisture.
•
The bottle of MEKINIST contains a desiccant packet to help keep your medicine dry. Do not throw away the desiccant packet.
•
Keep MEKINIST in its original bottle. Do not place tablets in a pill box.
•
Safely throw away MEKINIST that is out of date or no longer needed.
Keep MEKINIST and all medicine out of the reach of children.
General information about MEKINIST
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information Leaflet. Do not use MEKINIST for a condition for which it was not prescribed. Do not give MEKINIST to other people, even if they have the same symptoms that you have. It may harm them.
You can ask your healthcare provider or pharmacist for information about MEKINIST that is written for health professionals.
For more information, go to www.MEKINIST.com or call 1-888-825-5249.
What are the ingredients in MEKINIST?
Active ingredient: trametinib
Inactive ingredients:
Tablet Core: mannitol, microcrystalline cellulose, hypromellose, croscarmellose sodium, magnesium stearate (vegetable source), sodium lauryl sulfate, colloidal silicon dioxide. Tablet Coating: hypromellose, titanium dioxide, polyethylene glycol, polysorbate 80 (2-mg tablets), iron oxide yellow (0.5-mg tablets), iron oxide red (2-mg tablets).
This Patient Information has been approved by the U.S. Food and Drug Administration.
MEKINIST is a trademark of GlaxoSmithKline.
GlaxoSmithKline
Research Triangle Park, NC 27709
©2013, GlaxoSmithKline. All rights reserved.
Issued: May 2013
MKN:1PIL
Principal Display Panel
NDC 0173-0849-13
Mekinist™
(trametinib) Tablets
0.5 mg*
Rx only
30 Tablets
*Each tablet contains 0.5635 mg trametinib dimethyl sulfoxide equivalent to 0.5 mg of trametinib.
Dosage: See accompanying prescribing information.
Store refrigerated at 2° and 8°C (36° to 46°F).
Do not freeze.
Dispense in original bottle. Do not remove desiccant. Protect from moisture and light. Do not place medication in pill boxes.
GlaxoSmithKline
Research Triangle Park, NC 27709
Made in Singapore
10000000109892 Rev. 5/13
Principal Display Panel
NDC 0173-0858-13
Mekinist™
(trametinib) Tablets
1 mg*
Rx only
30 Tablets
*Each tablet contains 1.127 mg trametinib dimethyl sulfoxide equivalent to 1 mg of trametinib.
Dosage: See accompanying prescribing inf
