Tacrolimus capsules may cause serious side effects, including:

•See “What is the most important information I should know about Tacrolimus capsules?
•”high blood sugar (diabetes). Your doctor may do certain tests to check for diabetes while you take Tacrolimus capsules. Call your doctor right away if you have:
◦frequent urination
◦increased thirst or hunger
◦blurred vision
◦confusion
◦drowsiness
◦loss of appetite
◦fruity smell on your breath
◦nausea, vomiting, or stomach pain
•kidney problems. Your doctor may do certain tests to check your kidney function while you take Tacrolimus capsules.
•nervous system problems. Call your doctor right away if you get any of these symptoms while taking Tacrolimus capsules. These could be signs of a serious nervous system problem:
◦confusion
◦coma
◦muscle tremors
◦numbness and tingling
◦headache
◦seizures
◦vision changes
•high levels of potassium in your blood. Your doctor may do certain tests to check your potassium level while you take Tacrolimus capsules.
•high blood pressure. Your doctor will monitor your blood pressure while you take Tacrolimus capsules.
•heart problems (myocardial hypertrophy). Tell your doctor right away if you get any of these symptoms of heart problems while taking Tacrolimus capsules:
◦shortness of breath
◦chest pain
◦feel lightheaded
◦feel faint
The most common side effects of Tacrolimus capsules in people receiving kidney transplant are:

•infection
•tremors (shaking of the body)
•high blood pressure
•kidney problems
•constipation
•diarrhea
•headache
•stomach pain
•trouble sleeping
•nauseal
•ow levels of phosphate in your blood
•swelling of the hands, ankles, or legs
•weakness
•pain
•high levels of fat in your blood
•high levels of potassium in your blood
•low red blood cell count (anemia)
The most common side effects of Tacrolimus capsules in people receiving liver transplants are:

•shaking of the body tremors
•headache
•diarrhea
•high blood pressure
•nausea
•kidney problems
•stomach pain
•trouble sleeping
•numbness or tingling in your hands or feet
•anemia
•pain
•fever
•weakness
•high levels of potassium in the blood
•low levels of magnesium in the blood
The most common side effects of Tacrolimus for heart transplant patients are:

•kidney problems
•high blood pressure
Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Tacrolimus capsules. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088