H.P. ACTHAR(repository corticotropin)injection(十三)
isol on its own (adrenal insufficiency). Your child may need to take steroid medicine to protect the body until the adrenal gland recovers and is working well again, especially to protect the body if they have surgery or trauma. Do not stop giving your child injections of H.P. Acthar Gel without talking to your doctor first. Your doctor will tell you when and how to slowly stop giving the injections to avoid serious side effects.
While slowly stopping your child’s injections of H.P. Acthar Gel or after you stop giving the injections, call your doctor right away if your child has any of the following:
appears weak
loses weight or has a decrease in appetite
appears pale
has stomach pain
appears sick or is with fever
3. Effects on the adrenal gland while taking H.P. Acthar Gel
When your child is taking H.P. Acthar Gel, his or her adrenal gland may produce too much cortisol. This can cause symptoms of Cushing’s syndrome. Cushing’s syndrome is more common in children who take H.P. Acthar Gel for a long time.
Symptoms of Cushing’s syndrome include:
increased upper body fat around the neck, but not the arms and legs
weight gain
rounded or "moon" face
thin skin, easy bruising, and stretch marks on thighs, belly and trunk
slowed growth rates in children
weak bones (osteoporosis)
While receiving treatment with H.P. Acthar Gel other side effects can happen that are like side effects that happen due to treatment with steroid medicines. The risk of getting side effects may increase the longer your child is treated with H.P. Acthar Gel. Side effects may include:
increased blood pressure.Your doctor may check your child’s blood pressure during treatment. If your child’s blood pressure increases, your doctor may talk with you about possible treatment choices.
too much water in the body (water retention), increased amount of body salts, and low potassium in the blood. H.P. Acthar Gel may cause your child to have an increased amount of body salts and water that stays in the body, and may lower the amount of potassium in your child’s blood. Follow your doctor’s instructions about if you need to decrease your child’s salt intake or if you need to feed your child foods high in potassium.
4. Your child should not receive certain vaccines during treatment with H.P. Acthar Gel.Your child may receive killed or inactivated vaccines while receiving H.P. Acthar Gel. Before your child receives any vaccines, talk to your doctor about which vaccines are safe for your child. Certain vaccines could cause your child to have serious side effects, or the vaccine may not be effective.
5. Hiding (masking) symptoms of other conditions or diseases.It may be more difficult for your doctor to diagnose other conditions or diseases in your child during treatment with H.P. Acthar Gel. During treatment and after treatment ends, tell your doctor if your child has:
any signs or symptoms of infection. See number 1 of this section in the Medication Guide.
changes in body weight
bloody or black tarry stool
vomiting
stomach pain
excessive tiredness
increased thirst
fast heart rate
difficulty breathing
6. Stomach and intestinal problems. H.P. Acthar Gel may cause bleeding of the stomach or intestine. Your child has an increased risk for bleeding from the stomach or having a stomach ulcer. Tell your doctor if your child has any pain in the stomach area (abdominal pain), vomits blood, or has bloody or black st |
